Department of Gynecology and Obstetrics, The University of Hong Kong-Shenzhen Hospital, 1, Haiyuan 1st Road, Futian District, Shenzhen, 518053, Guangdong, China.
Department of Gynecology and Obstetrics, Queen Elizabeth Hospital, 30 Gascoigne Road, Jordon, Kowloon, Hong Kong, China.
Int Urogynecol J. 2022 Jan;33(1):3-13. doi: 10.1007/s00192-021-04823-w. Epub 2021 Jun 3.
Sacrocolpopexy and sacrospinous ligament fixation (SSLF) have been used for the restoration of apical support. Studies comparing sacrocolpopexy and SSLF have reported conflicting results. We aim to assess the current evidence regarding efficiency and the complications of sacrocolpopexy compared with SSLF.
We searched PubMed, Embase, and Cochrane Library and performed a systematic review meta-analysis to assess the two surgical approaches.
5Five randomized controlled trials, 8 retrospective studies, and 2 prospective studies including 4,120 cases were identified. Compared with abdominal sacrocolpopexy (ASC), SSLF was associated with a lower success rate (88.32% and 91.45%; OR 0.52; 95% CI 0.29-0.95; p = 0.03), higher recurrence (11.58% and 8.32%; OR 1.97; 95% CI 1.04-3.46; p = 0.04), and dyspareunia rate (14.36% and 4.67%; OR 3.10; 95% CI 1.28-7.50; p = 0.01). Patients in this group may benefit from shorter operative time (weighted mean difference -25.08 min; 95% CI -42.29 to -7.88; p = 0.004), lower hemorrhage rate (0.85% and 2.58%; OR 0.45; 95% CI 0.25-0.85; p = 0.009), wound infection rate (3.30% and 5.76%; OR 0.55; 95% CI 0.39-0.77; p = 0.0005), and fewer gastrointestinal complications (1.33% and 6.19%; OR 0.33; 95% CI 0.15-0.76; p = 0.009).
Both sacrocolpopexy and SSLF offer an efficient alternative to the restoration of apical support. When anatomical durability and sexual function is a priority, ASC may be the preferred option. When considering factors of mesh erosion, operative time, gastrointestinal complications, hemorrhage, and wound infections, SSLF may be the better option.
骶骨阴道固定术(colpopexy)和骶骨棘韧带固定术(SSLF)已被用于恢复子宫顶的支撑。比较骶骨阴道固定术和骶骨棘韧带固定术的研究报告结果相互矛盾。我们旨在评估关于骶骨阴道固定术与骶骨棘韧带固定术的效率和并发症的现有证据。
我们搜索了 PubMed、Embase 和 Cochrane Library,并进行了系统评价荟萃分析,以评估这两种手术方法。
共确定了 5 项随机对照试验、8 项回顾性研究和 2 项前瞻性研究,共纳入 4120 例病例。与腹式骶骨阴道固定术(ASC)相比,骶骨棘韧带固定术的成功率较低(88.32%和 91.45%;OR 0.52;95%CI 0.29-0.95;p=0.03),复发率较高(11.58%和 8.32%;OR 1.97;95%CI 1.04-3.46;p=0.04),性交困难发生率较高(14.36%和 4.67%;OR 3.10;95%CI 1.28-7.50;p=0.01)。该组患者可能受益于手术时间更短(加权均数差-25.08 分钟;95%CI-42.29 至-7.88;p=0.004)、出血量更少(0.85%和 2.58%;OR 0.45;95%CI 0.25-0.85;p=0.009)、伤口感染率较低(3.30%和 5.76%;OR 0.55;95%CI 0.39-0.77;p=0.0005)和较少的胃肠道并发症(1.33%和 6.19%;OR 0.33;95%CI 0.15-0.76;p=0.009)。
骶骨阴道固定术和骶骨棘韧带固定术均为恢复子宫顶支撑的有效替代方法。当解剖学耐久性和性功能是优先考虑因素时,ASC 可能是首选。当考虑网片侵蚀、手术时间、胃肠道并发症、出血和伤口感染等因素时,骶骨棘韧带固定术可能是更好的选择。