单侧散发性视网膜母细胞瘤患儿进展性Chiari I型畸形的发生
Development of Progressive Chiari I Malformation in a Child with Unilateral Sporadic Retinoblastoma.
作者信息
Karimi Saeed, Arabi Amir, Shahraki Toktam, Ansari Iman, Safi Sare
机构信息
Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Ophthalmology, Torfeh Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
J Curr Ophthalmol. 2021 Mar 26;33(1):88-90. doi: 10.4103/JOCO.JOCO_166_20. eCollection 2021 Jan-Mar.
PURPOSE
To report a case of progressive Chiari malformation type I (CIM) in a patient with unilateral sporadic retinoblastoma (RB) treated with intra-arterial chemotherapy (IAC) and enucleation.
METHODS
A 5-year-old male patient with a history of RB in his left eye treated with IAC and enucleation presented to our clinic for routine RB surveillance. Radiotherapy had not been used for the treatment of his RB.
RESULTS
A progressive herniation of cerebellar tonsils through the foramen magnum was detected on follow-up magnetic resonance imaging (MRI). Brain and cervical MRI revealed no central nervous system mass, hydrocephalus, or syringomyelia. There was no history of head trauma.
CONCLUSION
Progressive CIM may occur in unilateral sporadic RB.
目的
报告1例接受动脉内化疗（IAC）和眼球摘除术治疗的单侧散发性视网膜母细胞瘤（RB）患者发生的进行性I型Chiari畸形（CIM）病例。
方法
一名5岁男性患者，左眼有RB病史，接受了IAC和眼球摘除术，前来我院进行RB常规监测。其RB治疗未采用放疗。
结果
随访磁共振成像（MRI）检测到小脑扁桃体经枕骨大孔进行性疝出。脑部和颈部MRI未显示中枢神经系统肿块、脑积水或脊髓空洞症。无头部外伤史。
结论
进行性CIM可能发生于单侧散发性RB。
Zotero 插件