Department of Neurology, University of Louisville School of Medicine, 500 S Preston St, 113-a HSC, Louisville, KY, 40202, USA.
Norton Children's Neuroscience Institute, Norton Healthcare, Louisville, KY, USA.
Curr Pain Headache Rep. 2021 Jun 4;25(8):51. doi: 10.1007/s11916-021-00967-y.
Post-traumatic headache is a common disorder in the pediatric age group, seen both by child neurologists and by non-neurologists. The current review of post-traumatic headache in children and adolescents aims to review the pathophysiology, risk factors, clinical features, neuroimaging, and both acute and preventive treatment options.
Recent literature provides insight into specific risk factors in the pediatric age group for developing post-traumatic headache as well as unique pathophysiologic changes seen in neuroimaging and neurometabolic pathways. It also elucidates common treatment options and novel treatments being currently explored, such as with monoclonal antibodies to CGRP. Finally, current evidence and guidelines recommend the benefit of a gradual return to normal activity based on symptom stability rather than a specific time period. Review of literature on pediatric post-traumatic headache reveals a growing understanding of the factors involved in developing headache after head trauma and the diagnosis/treatment of headache though future research will help further elucidate these areas.
创伤后头痛是儿童期常见疾病,儿童神经病学家和非神经病学家均可诊断。本综述旨在回顾儿童和青少年创伤后头痛的发病机制、危险因素、临床特征、神经影像学以及急性和预防性治疗选择。
近期文献深入探讨了儿童期发生创伤后头痛的特定危险因素,以及神经影像学和神经代谢途径中观察到的独特病理生理变化。它还阐明了常见的治疗选择和目前正在探索的新治疗方法,例如使用降钙素基因相关肽单克隆抗体。最后,目前的证据和指南建议根据症状稳定性而不是特定时间段逐渐恢复正常活动,以有益于头痛的诊断和治疗。对儿童创伤后头痛的文献综述揭示了对创伤后头痛发生相关因素以及头痛诊断/治疗的认识不断提高,但未来的研究将有助于进一步阐明这些领域。