心脏直视手术后 C 反应蛋白反应受损的 1 例罕见病例：病例报告及文献复习。
A novel case of impaired C-reactive protein response following open-heart surgery: A case report and review of the literature.
机构信息
Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
出版信息
Clin Chim Acta. 2021 Sep;520:196-201. doi: 10.1016/j.cca.2021.06.007. Epub 2021 Jun 4.
BACKGROUND
C-reactive protein (CRP) is expected to increase in response to a range of inflammatory stimuli such as infections or extensive tissue trauma.
CASE REPORT
We present a novel case of severely impaired CRP response following NSTEMI, influenza A infection and open-heart surgery in which serum CRP concentrations remained < 1 mg/L during an observational period of 28 days.
CONCLUSION
To our knowledge, no previous publications exists describing patients with a lack of CRP response following cardiothoracic surgery. We believe this to be a novel finding warranting further investigations regarding the etiology and prevalence of this phenomenon.
背景
C 反应蛋白（CRP）预计会在一系列炎症刺激下增加，例如感染或广泛的组织创伤。
病例报告
我们报告了一例新型 NSTEMI、甲型流感感染和心脏直视手术后 CRP 反应严重受损的病例，在 28 天的观察期内，血清 CRP 浓度一直<1mg/L。
结论
据我们所知，以前没有文献描述过心脏直视手术后 CRP 反应缺乏的患者。我们认为这是一个新的发现，需要进一步研究这种现象的病因和普遍性。
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