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血清阳性医护人员完成 BNT162b2 全程接种后出现有症状的 SARS-CoV-2 感染:来自单一机构的病例系列研究。

Symptomatic SARS-CoV-2 infections after full schedule BNT162b2 vaccination in seropositive healthcare workers: a case series from a single institution.

机构信息

Department of Medicine and Surgery, University of Insubria, Varese, Italy.

Laboratory of Microbiology, ASST dei Sette Laghi, Varese, Italy.

出版信息

Emerg Microbes Infect. 2021 Dec;10(1):1254-1256. doi: 10.1080/22221751.2021.1942230.

Abstract

We report 11 cases of SARS-CoV-2 infection in healthcare workers (HCW) for COVID-19 and seropositive after the second dose of the BNT162b2 mRNA vaccine. Based on voluntary-based surveillance, they tested positive for different strains of SARS-CoV-2, as Spike gene sequencing showed. Five of them reported mild symptoms. Given the risk for SARS-CoV-2 introduction from asymptomatic vaccinees, this case series suggests the need to continue nasopharyngeal screening programmes.

摘要

我们报告了 11 例 COVID-19 期间 SARS-CoV-2 感染的医护人员(HCW),他们在接种第二剂 BNT162b2 mRNA 疫苗后血清呈阳性。基于自愿监测,根据 Spike 基因测序显示,他们感染了不同的 SARS-CoV-2 毒株。其中 5 人报告有轻微症状。鉴于无症状疫苗接种者引入 SARS-CoV-2 的风险,本病例系列表明需要继续进行鼻咽筛查计划。

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