Department of Radiation Oncology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
J Cancer Res Ther. 2021 Apr-Jun;17(2):303-310. doi: 10.4103/jcrt.JCRT_841_19.
Dose-escalated prostate radiotherapy (RT) can improve treatment outcomes, but rectal toxicity is the main limiting factor for introducing dose-escalated RT. Pushing rectal wall away from the prostate reduces the volume of the rectum in high-dose region, which can decrease both short- and long-term rectal toxicities after RT. This review focuses on the literature using different rectal displacement devices such as endorectal balloons, tissue spacers, rectal retractor, and ProSpare during prostate External beam radiotherapy, with regard to dosimetric effects, clinical benefits, prostate motion, and postoperative RT setting.
调强前列腺放射治疗(RT)可以改善治疗效果,但直肠毒性是引入调强 RT 的主要限制因素。将直肠壁从前列腺推开可以减少高剂量区域的直肠体积,从而降低 RT 后短期和长期直肠毒性。本文综述了在前列腺外照射放疗中使用不同的直肠移位装置,如内直肠球囊、组织间隔物、直肠牵开器和 ProSpare,以及它们在剂量学效果、临床获益、前列腺运动和术后 RT 设定方面的研究进展。