Hoshiyama Akihiro, Kawanishi Hiroaki, Takahashi Takehiro, Takamori Hajime, Takashima Yasushi, Kono Yuka, Okumura Kazuhiro, Fujita Kumi, Sumiyoshi Shinji
The Department of Urology, Tenri Hospital.
The Department of Diagnostic Pathology, Tenri Hospital.
Hinyokika Kiyo. 2021 May;67(5):191-195. doi: 10.14989/ActaUrolJap_67_5_191.
75 year-old man followed up regularly for the treatment of lung cancer came to our hospital with a chief complaint of general malaise. Blood test results showed deterioration in the renal function, and computed tomography (CT) confirmed left hydronephrosis. He was admitted to the hospital with the diagnosis of obstructive pyelonephritis. Despite antibiotic therapy after the left ureteral stent placement, CT on day 19 of hospitalization showed an enlarged soft tissue shadow along the renal pelvis and ureter, which was suspected to be peripelvic urinary extravasation caused by stent occlusion. We decided that conservative treatment would not improve his condition and conducted surgical therapy considering the possibility of malignancy. Intraoperatively, viscous and fragile tumor affected the renal pelvis and ureter. The operation resulted in left nephrectomy because radical resection was impossible. The pathological diagnosis was sarcomatoid urothelial carcinoma of the renal pelvis with ureter origin. He died due to multipleorgan failureon day 20 after theope ration. Were port a caseof sarcomatoid urothelial carcinoma in the upper urinary tract that was difficult to diagnose preoperatively based on imaging studies.
一名75岁男性因肺癌接受定期治疗,因全身乏力为主诉前来我院。血液检查结果显示肾功能恶化,计算机断层扫描(CT)证实左肾积水。他因诊断为梗阻性肾盂肾炎入院。尽管在放置左输尿管支架后进行了抗生素治疗,但住院第19天的CT显示肾盂和输尿管沿线有增大的软组织阴影,怀疑是支架阻塞导致的肾盂周围尿外渗。我们认为保守治疗无法改善他的病情,考虑到恶性肿瘤的可能性,进行了手术治疗。术中,粘性且脆弱的肿瘤累及肾盂和输尿管。由于无法进行根治性切除,手术结果为左肾切除术。病理诊断为肾盂输尿管起源的肉瘤样尿路上皮癌。他在手术后第20天因多器官衰竭死亡。我们报告一例上尿路肉瘤样尿路上皮癌病例,术前基于影像学检查难以诊断。