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在无血运重建的情况下,机械左心室卸载改善了限制血流的自发性冠状动脉夹层的症状和冠状动脉灌注梯度。

Improvement of symptoms and coronary perfusion gradient with mechanical left ventricular unloading in flow-limiting complex spontaneous coronary artery dissection, without revascularization.

机构信息

Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.

出版信息

Catheter Cardiovasc Interv. 2021 Oct;98(4):E581-E585. doi: 10.1002/ccd.29836. Epub 2021 Jun 15.

Abstract

Spontaneous coronary artery dissection (SCAD) can lead to acute coronary syndrome and sudden cardiac death, particularly in young women. Observational data show that, in SCAD patients, both percutaneous coronary intervention and coronary artery bypass grafting seem to be hampered by higher technical complexity, lower success rates, and worse outcomes. As spontaneous healing is a common occurrence, expert consensus advices medical management of the acute phase, when feasible. We present the case of a young woman with SCAD of left anterior descending artery causing myocardial infarction with ST-segment elevation. High-anatomical complexity and unstable conditions of the patient made both medical management and immediate revascularization unfeasible options. Therefore, we decided to implant a percutaneous off-loading mechanical support device to improve coronary perfusion pressure by unloading the left ventricle and preserve cardiac function, preventing worse complications of acute myocardial infarction. This strategy was successful in stabilizing the patient, until the definitive revascularization treatment became an option.

摘要

自发性冠状动脉夹层(SCAD)可导致急性冠状动脉综合征和心源性猝死,尤其是在年轻女性中。观察性数据显示,在 SCAD 患者中,经皮冠状动脉介入治疗和冠状动脉旁路移植术似乎都因技术复杂性较高、成功率较低和预后较差而受到阻碍。由于自发性愈合较为常见,专家共识建议在可行的情况下对急性阶段进行药物治疗。我们报告了一例左前降支 SCAD 导致 ST 段抬高型心肌梗死的年轻女性病例。患者解剖结构复杂,病情不稳定,药物治疗和即刻血运重建均不可行。因此,我们决定植入经皮卸载机械辅助装置,通过减轻左心室负荷来提高冠状动脉灌注压,保护心功能,防止急性心肌梗死的更严重并发症。这一策略成功稳定了患者病情,直到可以进行明确的血运重建治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/202e/8518797/091aadccae19/CCD-98-E581-g001.jpg

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