Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Urol J. 2021 Jun 15;19(4):325-328. doi: 10.22037/uj.v18i.6556.
PURPOSE: To assess the prognostic effect of blood urea nitrogen to serum albumin ratio in patients with Fournier's gangrene (FG) in a referral center in order to reduce the mortality of FG patients. MATERIALS AND METHODS: Patients with FG were admitted and enrolled consecutively in this study from March 2008 to April 2020. Statistical analysis was done to evaluate the differences between the two groups and to identify the best cutoff value to predict mortality and the need for intensive care. RESULTS: Of all 114 patients, 46 patients (40.35%) died in the course of hospitalization and 40 entered the study. No variable manifested a notable difference except for the BUN to albumin ratio, which was significantly different (P-value = 0.045). The ratio of BUN to albumin was not associated with any other variables and was independently a predictor of death in FG patients. CONCLUSION: The ratio of BUN to albumin was significantly different among deceased and survived patients with FG. Therefore, more studies with a larger sample size are still needed to access this parameter properly.
目的：在一家转诊中心评估血尿素氮与血清白蛋白比值对 Fournier 坏疽（FG）患者的预后影响，以降低 FG 患者的死亡率。
材料和方法：本研究于 2008 年 3 月至 2020 年 4 月连续纳入 FG 患者，并进行统计分析，以评估两组之间的差异，确定预测死亡率和需要重症监护的最佳截断值。
结果：在所有 114 名患者中，46 名（40.35%）在住院期间死亡，40 名进入研究。除了血尿素氮与白蛋白比值外，没有任何变量表现出显著差异（P 值=0.045）。血尿素氮与白蛋白比值与任何其他变量均无相关性，是 FG 患者死亡的独立预测因素。
结论：死亡和存活的 FG 患者的血尿素氮与白蛋白比值有显著差异。因此，仍需要更多的大样本量研究来正确评估该参数。
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