Bahar İlhan, Oksuz Hafize, Şenoğlu Nimet, Demirkiran Hilmi, Aydoğan Mustafa, Tomak Yakup, Çömez Mehmet, Bayrakçı Sinem, Gönüllü Edip, Berktaş Mustafa
Anesthesiology and Reanimation, Bakırçay University Çiğli Training and Research Hospital, Izmir, TUR.
Anesthesiology and Reanimation, Kahramanmaraş Sütçü imam University Faculty of Medicine, Kahramanmaraş, TUR.
Cureus. 2021 May 12;13(5):e14989. doi: 10.7759/cureus.14989.
Objectives Sepsis bundle compliance is not clear. We evaluated rates of compliance with sepsis bundle protocols among health care providers in Turkey. Methods Our study was carried out retrospectively. Forty-five intensive care units (ICU) participated in this study between March 2, 2018 and October 1, 2018. Results One hundred thirty-eight ICUs were contacted and 45 ICUs agreed to participate. The time taken for the diagnosis of sepsis was less than six hours in 384 (59.8%) patients, while it was more than six hours in 258 (40.2%) patients. The median [interquartile range (IQR)] times for initial antibiotic administration, culturing, vasopressor initiation, and second lactate measurement were 120.0 (60-300) minutes, 24 (12-240) minutes, 40 (20-60) minutes, and 24 (18-24) hours, respectively. The rate of compliance with tissue and organ perfusion follow-up in the first six hours was 0%. The rates of three- and six-hour sepsis bundle protocol compliance were both 0%. The ICU mortality rates for sepsis and septic shock were 22% and 78%, respectively. The ICU mortality rates for sepsis and septic shock were 22% and 78%, respectively. Conclusions The rate of compliance with sepsis bundle protocols was evaluated in Turkey for the first time and determined to be 0%.
目的 脓毒症集束化治疗的依从性尚不清楚。我们评估了土耳其医疗服务提供者对脓毒症集束化治疗方案的依从率。方法 我们的研究为回顾性研究。2018年3月2日至2018年10月1日期间,45个重症监护病房(ICU)参与了本研究。结果 我们联系了138个ICU,其中45个同意参与。384例(59.8%)患者诊断脓毒症的时间少于6小时,而258例(40.2%)患者诊断脓毒症的时间超过6小时。初始抗生素给药、培养、血管活性药物启动和第二次乳酸测量的中位[四分位间距(IQR)]时间分别为120.0(60 - 300)分钟、24(12 - 240)分钟、40(20 - 60)分钟和24(18 - 24)小时。前6小时组织和器官灌注随访的依从率为0%。3小时和6小时脓毒症集束化治疗方案的依从率均为0%。脓毒症和脓毒性休克的ICU死亡率分别为22%和78%。结论 首次在土耳其评估了脓毒症集束化治疗方案的依从率,结果为0%。