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免疫缺陷患儿播散性曲霉病合并心肌脓肿。

Disseminated Aspergillosis Complicated With a Myocardial Abscess in an Immunodeficient Child.

机构信息

Department of Pediatric and Congenital Cardiology, M3C Regional Reference Center.

Departments of Pediatric Radiology.

出版信息

J Pediatr Hematol Oncol. 2021 Aug 1;43(6):226-227. doi: 10.1097/MPH.0000000000002078.

Abstract

Aspergillosis infection is a major complication of acquired immunosuppression, and is associated with poor prognosis in its invasive form. Cardiac dissemination of invasive aspergillosis is a rare and usually fatal consequence of systemic mycosis. We describe a pediatric case of myocardial aspergillosis abscess in a 12-year-old girl diagnosed with multimodality cardiac imaging approach. The patient underwent prolonged antimycotic treatment and bone marrow transplant, which improved her immunity, and, for the first time in the literature, resulted in a favorable outcome.

摘要

曲霉菌感染是获得性免疫抑制的主要并发症,侵袭性形式与预后不良相关。侵袭性曲霉菌病的心脏播散是系统性真菌感染的罕见且通常致命的后果。我们描述了一例 12 岁女孩心肌曲霉菌脓肿的儿科病例,该患者通过多模态心脏成像方法进行诊断。该患者接受了长期抗真菌治疗和骨髓移植,这改善了她的免疫力,并在文献中首次取得了良好的结果。

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