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病例报告:多模态成像作为瓦尔萨尔瓦窦纤维弹性瘤致命定位的生命线

Case Report: Multimodality Imaging as a Lifeline for Fatal Localization of Valsalva Sinus Fibroelastoma.

作者信息

Tadic Snezana, Ilic Aleksandra, Stefanovic Maja, Stojsic-Milosavljevic Anastazija, Popov Tanja, Bjelobrk Marija, Milovancev Aleksandra, Maksimovic Nebojsa, Drid Patrik

机构信息

Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.

Department of Electrocardiography, Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia.

出版信息

Front Cardiovasc Med. 2021 May 31;8:683534. doi: 10.3389/fcvm.2021.683534. eCollection 2021.

Abstract

Papillary fibroelastomas are rare benign heart tumors, and is most likely to involve the cardiac valves. We will present an extremely rare localization of a large Valsalva sinus fibroelastoma, with occasional left coronary artery ostial obstruction presented as an acute coronary syndrome. The tumor was removed surgically and histologically confirmed as papillary fibroelastoma. This review points to the crucial importance of multidisciplinary team decision and multimodality imaging methods for diagnosing the fibroelastoma, determination of size, and localization, which avoided complications of fatal embolization during an invasive procedure. A healthy 55-year-old male with vigorous physical daily training and exercise was admitted to the acute coronary syndrome emergency department. Shortly after admission, expert transthoracic echocardiography was performed. Computed tomography of the chest observed a large irregular hypodense tumor-like lesion in the bulbar aorta that was occasionally prolapsing into the left main coronary artery ostium and which corresponded to fibroelastoma. A few hours after admission, an emergency cardiac surgery was performed with the excision of a Valsalva sinus tumor (size 2 × 2 cm) located between the right and left coronary cusp of the aortic valve. Focus cardiac ultrasound should be performed for any acute coronary syndrome because of the possible Valsalva sinus fibroelastoma etiology. Its localization next to the left main coronary artery ostium is rare, and dangerous. The timely diagnosis can be made by the multimodality imaging method, however, the final diagnosis will be made pathohistologically. Early cardiac surgery may be a necessitated recourse for these patients in order to prevent a fatal outcome.

摘要

乳头状纤维弹性瘤是一种罕见的心脏良性肿瘤,最常累及心脏瓣膜。我们将呈现一个极其罕见的大瓦氏窦纤维弹性瘤定位病例,该肿瘤偶尔导致左冠状动脉开口阻塞,表现为急性冠状动脉综合征。肿瘤通过手术切除,并经组织学确诊为乳头状纤维弹性瘤。本综述指出多学科团队决策和多模态成像方法对于诊断纤维弹性瘤、确定其大小和定位至关重要,这避免了侵入性操作过程中致命栓塞的并发症。一名身体健康、每天进行高强度体育锻炼的55岁男性因急性冠状动脉综合征被收入急诊科。入院后不久,进行了专家经胸超声心动图检查。胸部计算机断层扫描观察到球部主动脉有一个大的不规则低密度肿瘤样病变,偶尔脱垂至左冠状动脉主干开口处,符合纤维弹性瘤表现。入院后数小时,进行了急诊心脏手术,切除了位于主动脉瓣左右冠状瓣之间的瓦氏窦肿瘤(大小为2×2厘米)。对于任何急性冠状动脉综合征患者,由于可能存在瓦氏窦纤维弹性瘤病因,均应进行重点心脏超声检查。其位于左冠状动脉主干开口旁的定位罕见且危险。多模态成像方法可实现及时诊断,但最终诊断需依靠病理组织学检查。对于这些患者,早期心脏手术可能是必要的治疗手段,以防止出现致命后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d173/8200485/efbc6e29892e/fcvm-08-683534-g0001.jpg

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