磁共振扩散加权成像及液体衰减反转恢复序列用于肝脏包虫囊肿与单纯囊肿的鉴别诊断

Diffusion-weighted MRI and FLAIR sequence for differentiation of hydatid cysts and simple cysts in the liver.

作者信息

Yalcinoz Kursad, Ikizceli Turkan, Kahveci Servet, Karahan Okkes Ibrahim

机构信息

Elbistan State Hospital, Radiology Clinic, Kahramanmaras, Turkey.

University of Health Sciences, Istanbul Haseki Training and Research Hospital, Department of Radiology, Adnan Adivar Street, Number: 9, 34130, Fatih, Istanbul, Turkey.

出版信息

Eur J Radiol Open. 2021 May 31;8:100355. doi: 10.1016/j.ejro.2021.100355. eCollection 2021.

DOI:10.1016/j.ejro.2021.100355

PMID:34136590

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8181784/

Abstract

PURPOSE

The contribution of DWI and FLAIR to the differential diagnosis of type 1, 2, and 3 hydatid cysts and simple liver cysts was investigated according to the Gharbi classification. This study is the first report using FLAIR sequence for the differential diagnosis of liver hydatid cysts in this regard.

METHODS

A total of 82 hydatid cysts and 40 simple cysts were scanned with DWI (in b600-b1000 values) and FLAIR sequence. In 64 patients included in the study, a total of 122 cystic lesions were diagnosed histopathologically or during follow-up. FLAIR and DWI signal characteristics were evaluated, and ADC values were calculated.

RESULTS

The mean ADC value of hydatid cysts on DWI (b600) was 3.07 ± 0.41 × 10 s/mm, while it was 3.91 ± 0.51 × 10 s/mm for simple cysts and the difference was statistically significant (p < 0.05). On b1000 DWI, the mean ADC values of hydatid and simple cysts were 2.99 ± 0.38 × 10 s/mm and 3.43 ± 0:29 × 10 s/mm, respectively (p < 0.05). The qualitative evaluation of the signal intensity on b600-1000 DWI demonstrated the difference between the simple and hydatid cyst groups (p < 0.05). Type 2 hydatid cysts alone were distinguished from type 2-3 hydatid and simple cysts by FLAIR (p < 0.05).

CONCLUSIONS

ADC values can distinguish between hydatid cyst and simple cyst. FLAIR contributes to the differentiation of type 2 hydatid and simple cysts.

摘要

目的

根据加尔比分类法，研究弥散加权成像（DWI）和液体衰减反转恢复序列（FLAIR）在1型、2型和3型包虫囊肿与单纯肝囊肿鉴别诊断中的作用。本研究是在这方面首次使用FLAIR序列进行肝包虫囊肿鉴别诊断的报告。

方法

对82个包虫囊肿和40个单纯囊肿进行DWI（b值为600 - 1000）和FLAIR序列扫描。纳入研究的64例患者中，共有122个囊性病变经组织病理学诊断或随访确诊。评估FLAIR和DWI信号特征，并计算表观扩散系数（ADC）值。

结果

DWI（b600）上包虫囊肿的平均ADC值为3.07±0.41×10⁻³s/mm²，而单纯囊肿为3.91±0.51×10⁻³s/mm²，差异有统计学意义（p<0.05）。在b1000 DWI上，包虫囊肿和单纯囊肿的平均ADC值分别为2.99±0.38×10⁻³s/mm²和3.43±0.29×10⁻³s/mm²（p<0.05）。b600 - 1000 DWI上信号强度的定性评估显示单纯囊肿组与包虫囊肿组之间存在差异（p<0.05）。仅2型包虫囊肿可通过FLAIR与2 - 3型包虫囊肿及单纯囊肿区分开来（p<0.05）。