College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China.
Chem Commun (Camb). 2021 Jul 6;57(54):6584-6595. doi: 10.1039/d1cc02116h.
Taking advantage of activatable and imaging-guided properties, stimuli-activated molecular photothermal agents (MPTAs) have drawn great attention in photothermal therapy (PTT) over the past decades. In this review, the recent progress in the study of stimuli-activated MPTAs is summarized from different stimuli, including pH, bioactive small molecules, and enzymes. The features and challenges of stimuli-activated MPTAs are also discussed. This review aims to motivate readers to design and synthesise more efficient MPTAs.
利用可激活和成像引导特性，刺激激活的分子光热剂（MPTAs）在过去几十年的光热治疗（PTT）中引起了极大的关注。在这篇综述中，从不同的刺激物（包括 pH 值、生物活性小分子和酶）方面总结了刺激激活的 MPTAs 的最新研究进展。还讨论了刺激激活的 MPTAs 的特点和挑战。本文旨在激励读者设计和合成更有效的 MPTAs。
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