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肥胖、妊娠期糖尿病与妊娠结局的相关性:综述

Correlation between obesity, gestational diabetes mellitus, and pregnancy outcomes: an overview.

机构信息

Department of Clinical Pharmacy Girls Section, Prince Sattam Bin Abdul Aziz University, Alkharj, Saudia Arabia.

Department of Pharmaceutical Sciences, University of Kashmir, Srinagar, Jammu and Kashmir, India.

出版信息

Int J Adolesc Med Health. 2021 Jun 18;33(6):339-345. doi: 10.1515/ijamh-2021-0058.

Abstract

Obesity has been identified mainly as a raise in the body's adiposity leading to prolonged overshoot of caloric intake over expenditure. Obesity has significant health-altering implications which have been shown to be implicated in the pathogenesis and progression of other diseases through its extensive physiological assaults. The prevalence of overweight and obesity has been an increasing epidemic worldwide. The number of obese births was even on the increase, with an increasing number of women of reproductive age registering as obese. Obesity is related to adverse perinatal outcomes and increased morbidity and mortality in pregnant women. The potential risk for multiple antenatal, postpartum, intrapartum, and neonatal complications is maternal obesity. Greater risk of developing Gestational Diabetes Mellitus (GDM), pregnancy induced hypertension (PIH), pre-eclampsia, risk of venous embolism, increased need for labor induction, and cesarean sections in the mother have been recorded in a comprehensive analysis of pregnancy complications associated with obesity. The link between obesity, gestational diabetes, and pregnancy outcomes will be briefly shown in this article.

摘要

肥胖主要被认为是体内脂肪增加,导致热量摄入超过支出的持续过度。肥胖对健康有重大影响,通过广泛的生理攻击,已被证明与其他疾病的发病和进展有关。超重和肥胖的患病率在全球范围内呈上升趋势。肥胖出生的人数甚至在增加,越来越多的育龄妇女被登记为肥胖。肥胖与不良围产期结局以及孕妇发病率和死亡率增加有关。多种产前、产后、产时和新生儿并发症的潜在风险与产妇肥胖有关。在对与肥胖相关的妊娠并发症进行综合分析后发现,肥胖的母亲患妊娠期糖尿病(GDM)、妊娠高血压(PIH)、子痫前期、静脉栓塞风险增加、需要更多引产和剖宫产的风险更高。本文将简要介绍肥胖、妊娠期糖尿病和妊娠结局之间的联系。

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