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肝囊型包虫内囊摘除术后肝门胆管狭窄的诊断和治疗方法。

Diagnosis and treatment modalities of hilar biliary duct stricture in hepatic cystic echinococcosis after endocystectomy.

机构信息

Department of Hepatobiliary and Echinococcosis Surgery, Digestive and Vascular Surgery Center, First Affiliated Hospital of Xinjiang Medical University, 830054 Urumqi, Xinjiang, PR China.

Department of Hepatobiliary and Echinococcosis Surgery, Digestive and Vascular Surgery Center, First Affiliated Hospital of Xinjiang Medical University, 830054 Urumqi, Xinjiang, PR China - State Key Laboratory of Pathogenesis, Prevention and Management of High Incidence Diseases in Central Asia, First Affiliated Hospital of Xinjiang Medical University, 830054 Urumqi, Xinjiang, PR China.

出版信息

Parasite. 2021;28:51. doi: 10.1051/parasite/2021051. Epub 2021 Jun 18.

Abstract

AIM

Hilar biliary duct stricture may occur in hepatic cystic echinococcosis (CE) patients after endocystectomy. This study aimed to explore diagnosis and treatment modalities.

METHODS

Clinical data of 26 hepatic CE patients undergoing endocystectomy who developed postoperative hilar biliary duct stricture were retrospectively analyzed and were classified into three types: type A, type B, and type C. Postoperative complications and survival time were successfully followed up.

RESULTS

Imaging showed biliary duct stenosis, atrophy of ipsilateral hepatic lobe, reactive hyperplasia, hepatic hilum calcification, and dilation or discontinuity of intrahepatic biliary duct. All patients received partial hepatectomy to resect residual cyst cavity and atrophic liver tissue, and anastomosis of hepatic duct with jejunum or common bile duct exploration was applied to handle hilar biliary duct stricture. Twenty-five patients were successfully followed up. Among type A patients, one patient died of organ failure, and upper gastrointestinal bleeding and liver abscess occurred in one patient. Moreover, calculus of intrahepatic duct was found in one type B and type C patient.

CONCLUSION

Long-term biliary fistula, infection of residual cavity or obstructive jaundice in hepatic CE patients after endocystectomy are possible indicators of hilar bile duct stricture. Individualized and comprehensive treatment measures, especially effective treatment of residual cavity and biliary fistula, are optimal to avoid serious hilar bile duct stricture.

摘要

目的

肝包虫内囊摘除术后可能发生肝门胆管狭窄。本研究旨在探讨其诊断和治疗方法。

方法

回顾性分析 26 例行肝包虫内囊摘除术的肝包虫病患者的临床资料,术后发生肝门胆管狭窄,分为 A、B、C 三型。术后并发症及生存时间成功随访。

结果

影像学表现为胆管狭窄、同侧肝叶萎缩、反应性增生、肝门钙化、肝内胆管扩张或中断。所有患者均行部分肝切除术切除残余囊腔和萎缩肝组织,行胆管与空肠或胆总管探查吻合术处理肝门胆管狭窄。25 例患者成功随访。A型患者中,1 例因多器官功能衰竭死亡,1 例发生上消化道出血和肝脓肿,1 例 B 型和 C 型患者发现肝内胆管结石。

结论

肝包虫内囊摘除术后长期胆瘘、残腔感染或阻塞性黄疸可能是肝门胆管狭窄的指标。个体化综合治疗措施,尤其是有效治疗残腔和胆瘘,是避免严重肝门胆管狭窄的最佳方法。

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