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直肠癌手术中加速康复外科(ERAS)实施障碍:与结肠癌手术比较分析。

Implementation barriers for Enhanced Recovery After Surgery (ERAS) in rectal cancer surgery: a comparative analysis of compliance with colon cancer surgeries.

机构信息

Colorectal Surgery Department, University Hospital Gregorio Marañón, Calle del Dr. Esquerdo, 46, Madrid, Spain.

Colorectal Surgery Department, University Hospital Fundación Jiménez Díaz, Madrid, Spain.

出版信息

Updates Surg. 2021 Dec;73(6):2161-2168. doi: 10.1007/s13304-021-01115-2. Epub 2021 Jun 18.

Abstract

We aim to analyze differences in compliance between colon and rectal cancer surgeries under Enhanced Recovery After Surgery (ERAS) for colorectal procedures, and to detect implementation barriers for rectal cancer surgeries. Patients who underwent elective rectal cancer surgeries under ERAS were case-matched based on gender, age, and P-POSSUM with an equal number of patients who underwent colonic surgeries. Achievements of ≥ 70% of ERAS items were considered an acceptable level of compliance. A multivariate analysis was carried out to identify independent risk factors for lower compliance. A total of 434 patients were included over a 5-year period. After matching, there were 111 patients in each group. Overall compliance was significantly lower in the rectal surgery group (73% vs 82%, p = 0.001). A good compliance rate differed from 55% in rectal vs 77.5% in colonic procedures (p = 0.000). We identified three independent risk factors for lower compliance rates: open surgical approach, the use of epidural catheter, and the presence of postoperative ileus. Our data showed that rectal cancer surgeries are more exigent to success on ERAS interventions when compared to colonic resections. There is a need to introduce specific modifications on the protocols for colorectal surgeries when applied to these particular procedures.

摘要

我们旨在分析结直肠手术中增强术后恢复(ERAS)下结肠癌和直肠癌手术的依从性差异,并发现直肠癌手术的实施障碍。根据性别、年龄和 P-POSSUM 对接受 ERAS 下择期直肠癌手术的患者进行病例匹配,使接受结直肠手术的患者数量相等。达到 ERAS 项目≥70%的患者被认为具有可接受的依从性水平。进行了多变量分析以确定依从性较低的独立危险因素。在 5 年期间共纳入了 434 名患者。匹配后,每组各有 111 名患者。总体依从性在直肠手术组明显较低(73%比 82%,p=0.001)。直肠手术的良好依从率为 55%,而结直肠手术的良好依从率为 77.5%(p=0.000)。我们确定了三个依从性较低的独立危险因素:开放手术方法、硬膜外导管的使用和术后肠梗阻的发生。我们的数据表明,与结直肠切除术相比,直肠癌手术对 ERAS 干预的成功要求更高。在将结直肠手术方案应用于这些特定手术时,需要引入特定的修改。

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