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矩形三点式泪点成形术与带硅胶管的泪点打孔成形术治疗后天性泪点狭窄的前瞻性随机对照研究

Rectangular 3-snip punctoplasty versus punch punctoplasty with silicone intubation for acquired external punctal stenosis: a prospective randomized comparative study.

作者信息

Cao Xin, Hu Zi-Zhong, Wu Ying, Song Yu, Liu Qing-Huai

机构信息

Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.

Department of Ophthalmology, the Second Affiliated Hospital of Nantong University, Nantong 226000, Jiangsu Province, China.

出版信息

Int J Ophthalmol. 2021 Jun 18;14(6):849-854. doi: 10.18240/ijo.2021.06.09. eCollection 2021.

Abstract

AIM

To evaluate the effectiveness of rectangular 3-snip punctoplasty versus punch punctoplasty Kelly punch with silicone intubation for the management of acquired external punctal stenosis (AEPS).

METHODS

A prospective, randomized, comparative study was performed on 123 eyes of 94 patients with AEPS. Patients were recruited into either group of rectangular 3-snip punctoplasty (group A) or group of punch punctoplasty with silicone intubation (group B). Outcomes measured were Munk score, grade of punctal stenosis, fluorescein dye disappearance time test (FDDT) and tear meniscus height (TMH) 6 and 12mo after surgery.

RESULTS

Twelve months after surgery, Munk score, FDDT and TMH significantly decreased in both groups compared with the baseline (all <0.05), and grade of punctal stenosis increased significantly (<0.05). The grade of punctal stenosis, Munk score, FDDT and TMH were better in group B compared with group A at 6 or 12mo (all <0.05). There was a positive correlation between TMH and Munk score (=0.655, <0.001). At the last followed-up, anatomical success was noted in 96.7% eyes in group A and 98.4% eyes in group B (=0.613).

CONCLUSION

Punch punctoplasty Kelly punch with silicone intubation achieves better outcomes than rectangular 3-snip punctoplasty. The new technique is a simple, minimally invasive, with high anatomical and functional success in patients with AEPS.

摘要

目的

评估矩形三点切开造口术与使用硅胶管插入的Kelly打孔造口术治疗获得性泪小点狭窄(AEPS)的有效性。

方法

对94例患有AEPS的患者的123只眼睛进行了一项前瞻性、随机、对照研究。患者被纳入矩形三点切开造口术组(A组)或硅胶管插入的打孔造口术组(B组)。测量的结果指标包括Munk评分、泪小点狭窄分级、荧光素染料消失时间试验(FDDT)以及术后6个月和12个月时的泪液半月高度(TMH)。

结果

术后12个月时,两组的Munk评分、FDDT和TMH均较基线显著降低(均P<0.05),泪小点狭窄分级显著增加(P<0.05)。在术后6个月或12个月时,B组的泪小点狭窄分级、Munk评分、FDDT和TMH均优于A组(均P<0.05)。TMH与Munk评分呈正相关(r=0.655,P<0.001)。在最后一次随访时,A组96.7%的眼睛和B组98.4%的眼睛获得了解剖学成功(P=0.613)。

结论

使用硅胶管插入的Kelly打孔造口术比矩形三点切开造口术取得更好的效果。这项新技术操作简单、微创,在治疗AEPS患者时具有较高的解剖学和功能成功率。

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本文引用的文献

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Eur J Ophthalmol. 2021 Mar;31(2):796-803. doi: 10.1177/1120672120925035. Epub 2020 May 19.
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