Cirugía General y del Aparato Digestivo, Hospital Universitario de Gran Canaria Doctor Negrín, España.
Anatomía Patológica, Hospital Universitario de Gran Canaria Doctor Negrín, España.
Rev Esp Enferm Dig. 2021 Nov;113(11):796-797. doi: 10.17235/reed.2021.7873/2021.
In relation to the article "A case of mixed adenoneuroendocrine tumor of the colon", we would like to contribute a new case of this exceptional and biphasic clinical entity - the MANEC (mixed adenoneuroendocrine carcinoma). These tumors represent a mix of pathological components, are highly aggressive, and affect the gastrointestinal and pancreatobiliary tract. They are characterized by the dual presence of glandular and neuroendocrine epithelial elements, where each component represents at least 30 % of the tumor.
关于“结肠混合性腺神经内分泌肿瘤病例”一文,我们想报告一例这种罕见的双相临床实体——MANEC(混合性腺神经内分泌癌)的新病例。这些肿瘤是多种病理成分的混合体,具有高度侵袭性,影响胃肠道和胰胆管。其特征是腺上皮和神经内分泌上皮成分的双重存在,其中每个成分至少占肿瘤的 30%。