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在非退伍军人健康管理局设施中寻求阿片类药物使用障碍非退伍军人事务部治疗的退伍军人中,药物辅助治疗与年龄和治疗完成情况的关联。

Association of Medication-Assisted Treatment and Age With Treatment Completion Among Veterans Seeking Non-VA Treatment for Opioid use Disorder at Non-Veterans Health Administration Facilities.

作者信息

Pickard Joseph G, van den Berk-Clark Carissa, Matthieu Monica M

机构信息

School of Social Work, University of Missouri-Saint Louis, 63121, USA.

Department of Family and Community Medicine, Saint Louis University School of Medicine, 63103, USA.

出版信息

Mil Med. 2022 Mar 28;187(3-4):504-512. doi: 10.1093/milmed/usab242.

Abstract

BACKGROUND

Medication-assisted treatment has been shown to be effective in treating opioid use disorder among both older adults and veterans of U.S. Armed Forces. However, limited evidence exists on MAT's differential effect on treatment completion across age groups. This study aims to ascertain the role of MAT and age in treatment completion among veterans seeking treatment in non-Department of Veterans Affairs healthcare facilities for opioid use disorder.

METHODS

We used the Treatment Episode Data Set-Discharges (TEDS-D; 2006-2017) to examine trends in treatment and MAT usage over time and TEDS-2017 to determine the role of age and MAT in treatment completion. We examined a subset of those who self-identified as veterans and who sought treatment for an opioid use disorder.

RESULTS

Veterans presented in treatment more often as heroin users than prescription opioid users, and older veterans were more likely to get MAT than younger veterans. We found that before propensity score matching, MAT initially appeared to be associated with a lower likelihood of treatment completion in inpatient ($\beta $ = -1.47, 95% CI -1.56 to -1.39) and outpatient ($\beta $ = -1.40, 95% CI -2.21 to -0.58) settings, and age (50+ years) appeared to mediate the effect of MAT on treatment completion ($\beta $ = -0.54, 95% CI -0.87 to -0.21). After matching, older veterans were more likely to complete substance use disorder treatment ($\beta $ = 0.21, 95% CI 0.01-0.42), while age no longer mediated the effect of MAT, and MAT had a significant positive impact on treatment completion in detox settings ($\beta $ = 1.36, 95% CI 1.15-1.50) and inpatient settings ($\beta $ = 1.54, 95% CI 1.37 -1.71).

CONCLUSION

The results show that age plays an important role in outpatient treatment completion, while MAT plays an important role in inpatient treatment completion. Implications for veterans are discussed.

摘要

背景

药物辅助治疗已被证明在治疗老年人和美国武装部队退伍军人的阿片类药物使用障碍方面有效。然而,关于药物辅助治疗对不同年龄组治疗完成率的差异影响的证据有限。本研究旨在确定药物辅助治疗和年龄在寻求非退伍军人事务部医疗保健设施治疗阿片类药物使用障碍的退伍军人治疗完成情况中的作用。

方法

我们使用治疗事件数据集-出院数据(TEDS-D;2006 - 2017年)来研究治疗和药物辅助治疗使用随时间的趋势,并使用2017年的TEDS数据来确定年龄和药物辅助治疗在治疗完成情况中的作用。我们研究了那些自我认定为退伍军人且因阿片类药物使用障碍寻求治疗的人群的一个子集。

结果

退伍军人在治疗中以海洛因使用者的身份出现的频率高于处方阿片类药物使用者,并且年长的退伍军人比年轻的退伍军人更有可能接受药物辅助治疗。我们发现,在倾向得分匹配之前,药物辅助治疗最初似乎与住院治疗(β = -1.47,95%置信区间 -1.56至 -1.39)和门诊治疗(β = -1.40,95%置信区间 -2.21至 -0.58)完成的可能性较低相关,并且年龄(50岁及以上)似乎介导了药物辅助治疗对治疗完成的影响(β = -0.54,95%置信区间 -0.87至 -0.21)。匹配后,年长的退伍军人更有可能完成物质使用障碍治疗(β = 0.21,95%置信区间0.01 - 0.42),而年龄不再介导药物辅助治疗的效果,并且药物辅助治疗在戒毒环境(β = 1.36,95%置信区间1.15 - 1.50)和住院环境(β = 1.54,95%置信区间1.37 - 1.71)中对治疗完成有显著的积极影响。

结论

结果表明年龄在门诊治疗完成中起重要作用,而药物辅助治疗在住院治疗完成中起重要作用。讨论了对退伍军人的影响。

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