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后路长节段融合联合椎体增强术后近端交界性后凸的生物力学研究。

A biomechanical study of proximal junctional kyphosis after posterior long segment fusion with vertebral body augmentation.

机构信息

Department of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.

Department of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.

出版信息

Clin Biomech (Bristol). 2021 Jul;87:105415. doi: 10.1016/j.clinbiomech.2021.105415. Epub 2021 Jun 23.

Abstract

Background Proximal junction kyphosis is a common clinical complication of posterior long-segment spinal fusion and vertebral body augmentation method is one of the effective approaches to prevent it. The purpose of this study was to explore the biomechanical effect of proximal junction kyphosis after posterior long-segment thoracolumbar fusion with different vertebral augmentation schemes using finite element analysis. Methods 3D nonlinear finite element models of T1-L5 spine posterior long-segment T8-L5 thoracolumbar fusion combined with T7, T8 and T7&T8 vertebral bone cement augmentation were constructed from human spine CT data and clinical surgical operation scheme to analyze the von Mises stress in the vertebrae, intervertebral discs pressure and pedicle screws system loads under the flexion, extension, lateral bending and axial rotation motion. Findings Compared with thoracolumbar posterior long-segment fusion model, T7 maximum stress in T7, T8 and T7&T8 vertebrae augmentation models were reduced by 8.64%, 7.17%, 8.51%;0.79%, -3.88%,1.67%;4.02%, 5.30%, 4.27% and 3.18%, 3.06%, -6.38% under the flexion, extension, lateral bending and axial rotation motion. T7/T8 intervertebral disc pressure in T7, T8, T7&T8 vertebral augmentation models were 36.71Mpa,29.78Mpa,36.47Mpa;22.25Mpa,18.35Mpa,22.06Mpa;84.27Mpa,68.17Mpa, 83.89Mpa and 52.23Mpa, 38.78Mpa,52.10Mpa under the same condition. The maximum stress 178.2Mpa of pedicle screws is mainly distributed at the root of screw. Interpretation Thoracolumbar posterior long-segment fusion with proximal double-segment vertebral augmentation should be recommended to prevent proximal junction kyphosis than single-segment augmentation. Simulation results can provide theoretical foundations and assist surgeons in selecting the appropriate operation scheme.

摘要

背景

近端交界性后凸是后路长节段脊柱融合的常见临床并发症,椎体增强是预防其发生的有效方法之一。本研究旨在通过有限元分析探讨后路长节段胸腰椎融合后采用不同椎体增强方案对近端交界性后凸的生物力学影响。

方法

基于人体脊柱 CT 数据和临床手术方案,构建 T1-L5 脊柱后路 T8-L5 胸腰椎融合联合 T7、T8 和 T7&T8 椎体骨水泥增强的三维非线性有限元模型,分析屈伸、侧屈和轴向旋转运动下椎体的 von Mises 应力、椎间盘压力和椎弓根螺钉系统载荷。

结果

与后路长节段胸腰椎融合模型相比,T7、T8 和 T7&T8 椎体增强模型中 T7 椎体的最大应力分别降低了 8.64%、7.17%、8.51%;0.79%、-3.88%、1.67%;4.02%、5.30%、4.27%和 3.18%、3.06%、-6.38%。在屈伸、侧屈和轴向旋转运动下,T7/T8 椎间盘压力在 T7、T8、T7&T8 椎体增强模型中分别为 36.71Mpa、29.78Mpa、36.47Mpa;22.25Mpa、18.35Mpa、22.06Mpa;84.27Mpa、68.17Mpa、83.89Mpa 和 52.23Mpa、38.78Mpa、52.10Mpa。在相同条件下,椎弓根螺钉的最大应力为 178.2Mpa,主要分布在螺钉根部。

结论

与单节段增强相比,后路长节段融合结合近段双节段椎体增强更有助于预防近端交界性后凸。模拟结果可为临床提供理论基础,辅助医生选择合适的手术方案。

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