Ariani Rojine, Ballas Leslie
Department of Radiation Oncology, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.
Case Rep Oncol. 2021 May 21;14(2):725-732. doi: 10.1159/000515780. eCollection 2021 May-Aug.
Primary CNS extranodal marginal zone B-cell lymphoma (MZBL) is a rare low-grade non-Hodgkin lymphoma characterized predominantly by small B cells, plasma cells, monocytoid cells, and scattered large immunoblasts. As a slow-growing tumor that remains localized, primary CNS MZBL carries an excellent clinical prognosis. Here, we report two cases of primary CNS MZBL successfully treated using external beam radiation therapy along with a literature review.
原发性中枢神经系统结外边缘区B细胞淋巴瘤(MZBL)是一种罕见的低度非霍奇金淋巴瘤,主要特征为小B细胞、浆细胞、单核样细胞和散在的大免疫母细胞。作为一种生长缓慢且局限于局部的肿瘤,原发性中枢神经系统MZBL具有良好的临床预后。在此,我们报告两例采用外照射放疗成功治疗的原发性中枢神经系统MZBL病例,并进行文献复习。