Department of Pulmonary Medicine, Kepler University Hospital, Krankenhausstraße 9, 4021, Linz, Austria.
Department of Anesthesiology and Intensive Care Medicine, Kepler University Hospital, Linz, Austria.
Wien Med Wochenschr. 2022 Jun;172(9-10):211-219. doi: 10.1007/s10354-021-00856-4. Epub 2021 Jun 29.
In December 2019, the new virus infection coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged. Simple clinical risk scores may improve the management of COVID-19 patients. Therefore, the aim of this pilot study was to evaluate the quick Sequential Organ Failure Assessment (qSOFA) score, which is well established for other diseases, as an early risk assessment tool predicting a severe course of COVID-19.
We retrospectively analyzed data from adult COVID-19 patients hospitalized between March and July 2020. A critical disease progress was defined as admission to intensive care unit (ICU) or death.
Of 64 COVID-19 patients, 33% (21/64) had a critical disease progression from which 13 patients had to be transferred to ICU. The COVID-19-associated mortality rate was 20%, increasing to 39% after ICU admission. All patients without a critical progress had a qSOFA score ≤ 1 at admission. Patients with a critical progress had in only 14% (3/21) and in 20% (3/15) of cases a qSOFA score ≥ 2 at admission (p = 0.023) or when measured directly before critical progression, respectively, while 95% (20/21) of patients with critical progress had an impairment oxygen saturation (SO) at admission time requiring oxygen supplementation.
A low qSOFA score cannot be used to assume short-term stable or noncritical disease status in COVID-19.
2019 年 12 月，由严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）引起的新型病毒感染冠状病毒病 2019（COVID-19）出现。简单的临床风险评分可能会改善 COVID-19 患者的管理。因此，本初步研究旨在评估快速序贯器官衰竭评估（qSOFA）评分，该评分已在其他疾病中得到很好的建立，作为预测 COVID-19 严重病程的早期风险评估工具。
我们回顾性分析了 2020 年 3 月至 7 月期间住院的成年 COVID-19 患者的数据。将危急疾病进展定义为入住重症监护病房（ICU）或死亡。
在 64 例 COVID-19 患者中，33%（21/64）发生危急疾病进展，其中 13 例患者需要转入 ICU。COVID-19 相关死亡率为 20%，ICU 入院后增加至 39%。所有无危急进展的患者入院时 qSOFA 评分均≤1。有危急进展的患者中，只有 14%（3/21）和 20%（3/15）的患者入院时 qSOFA 评分≥2（p=0.023）或在危急进展前直接测量时 qSOFA 评分≥2，而 95%（20/21）的有危急进展的患者在入院时需要氧饱和度（SO）下降，需要补充氧气。
低 qSOFA 评分不能用于假设 COVID-19 患者短期稳定或非危急疾病状态。
