Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen Denmark and Center for Healthy Aging, Department of Clinical Medicine, University of Copenhagen, Denmark.
Department of Physical and Occupational Therapy, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Scand J Med Sci Sports. 2021 Oct;31(10):1981-1990. doi: 10.1111/sms.14013. Epub 2021 Jul 14.
Loading intervention is currently the preferred management of tendinopathy, but to what extent different loading regimes influence the mechanical response in tendons is scarcely investigated. Therefore, the purposes of the investigation were to examine the effect of exercise interventions with either high or low load magnitude applied to the tendinopathic patellar tendon and the influence on its mechanical, material, and morphological properties. Forty-four men with chronic patellar tendinopathy were randomized to 12 weeks of exercising with either; 55% of 1RM throughout the period (MSR group) or 90% of 1RM (HSR group), and with equal total exercise volume in both groups. Mechanical (stiffness), material (T2* relaxation time), and morphological (cross-sectional area (CSA)) properties were assessed at baseline and after 12 weeks of intervention. MRI with ultra-short echo times (UTE) and T2*-mapping was applied to explore if T2* relaxation time could be used as a noninvasive marker for internal material alteration and early change thereof in response to intervention. There was no effect of HSR or MSR on the mechanical (stiffness), material (T2* relaxation time) or morphological (CSA) properties, but both regimes resulted in significant strength gain. In conclusion, there were no statistically superior effect of exercising with high (90%) compared to moderate (55%) load magnitude on the mechanical, material or morphological properties.
目前，加载干预是治疗腱病的首选方法，但不同的加载方式对肌腱力学反应的影响程度尚未得到充分研究。因此，本研究旨在探讨高负荷和低负荷两种运动干预方式对髌腱腱病的影响，以及对其力学、材料和形态特性的影响。44 名患有慢性髌腱腱病的男性被随机分为 12 周的运动治疗组，分别接受 1RM 的 55%（MSR 组）或 90%（HSR 组）的负荷，两组的总运动量相等。在基线和干预 12 周后评估力学（硬度）、材料（T2弛豫时间）和形态（横截面积（CSA））特性。应用超短回波时间（UTE）和 T2-mapping MRI 来探讨 T2弛豫时间是否可以作为一种非侵入性的标志物，用于评估内部材料变化及其对干预的早期变化。高负荷（90%）和中负荷（55%）运动治疗对力学（硬度）、材料（T2弛豫时间）或形态（CSA）特性均无显著影响，但两种治疗方案均显著增加了力量。总之，与中负荷（55%）相比，高负荷（90%）运动治疗对力学、材料或形态特性没有统计学上更优越的效果。
