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妊娠合并吉兰-巴雷综合征

Guillain-Barré syndrome in pregnancy.

作者信息

Hledíková Andrea, Hruban Lukáš, Jura René, Sas Igor, Hrdý Ondřej, Janků Petr

出版信息

Ceska Gynekol. 2021;86(3):189-193. doi: 10.48095/cccg2021189.

Abstract

OBJECTIVE

A case report of a 23-year-old pregnant woman diagnosed with Guillain-Barré syndrome in the 31st week of pregnancy.

CASE REPORT

We present a case study of a patient in the 31st week of pregnancy hospitalized at the University Hospital in Brno for expressed bulbar syndrome, neck muscle weakness, paresthesia of the arms and medical history of diarrhea in the previous week. During hospitalization, there was a rapid progression of symptoms and respiratory failure, requiring orotracheal intubation. The diagnosis of Guillain-Barré syndrome was determined and intravenous immunoglobulin therapy was initiated. The pregnancy was terminated in the 32nd week of gestation based on the maternal indication after a completed lung maturation of the fetus.

CONCLUSION

Guillain-Barré syndrome is a neurological disease that can rarely occur during pregnancy and puerperium. The syndrome presents a serious pregnancy complication with an uncertain prognosis and risk for both mother and fetus. If the syndrome is diagnosed in time and treated correctly, the prognosis is favorable despite the complicated course.

摘要

目的

报告一例23岁孕妇在妊娠31周时被诊断为吉兰-巴雷综合征的病例。

病例报告

我们呈现了一名妊娠31周患者的病例研究,该患者因明显的延髓综合征、颈部肌肉无力、手臂感觉异常以及前一周腹泻病史而入住布尔诺大学医院。住院期间,症状迅速进展并出现呼吸衰竭,需要进行口气管插管。确定诊断为吉兰-巴雷综合征,并开始静脉注射免疫球蛋白治疗。在胎儿肺成熟完成后,根据母亲的指征,在妊娠32周时终止妊娠。

结论

吉兰-巴雷综合征是一种在妊娠和产褥期很少发生的神经系统疾病。该综合征是一种严重的妊娠并发症,预后不确定,对母亲和胎儿都有风险。如果及时诊断并正确治疗,尽管病程复杂,预后仍良好。

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