突触长期增强过程中海马CA1神经元的异步突触反应。
Asynchronous synaptic responses in hippocampal CA1 neurons during synaptic long-term potentiation.
作者信息
Chirwa S S, Sastry B R
机构信息
Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
出版信息
Neurosci Lett. 1988 Jul 8;89(3):355-60. doi: 10.1016/0304-3940(88)90552-6.
PMID:3419633
Abstract
In guinea pig hippocampal slices incubated in Ba2+, stimulation of stratum radiatum induced an EPSP that was followed by an increased frequency of miniature EPSPs in CA1 neurons. These miniature EPSPS, which were presumably due to the asynchronous release of transmitter, were increased after the induction of long-term potentiation.
摘要
在含有钡离子的豚鼠海马切片中，刺激辐射层会诱发兴奋性突触后电位（EPSP），随后CA1神经元中微小兴奋性突触后电位（mEPSP）的频率增加。这些微小兴奋性突触后电位可能是由于递质的异步释放所致，在长期增强效应诱导后增加。
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