Farmakis Ioannis T, Demerouti Eftychia, Karyofyllis Panagiotis, Karatasakis George, Stratinaki Maria, Tsiapras Dimitrios, Athanassopoulos George, Voudris Vassilios, Giannakoulas George
Cardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, PC 54621 Thessaloniki, Greece.
Non-Invasive Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, Greece.
J Clin Med. 2021 Jun 26;10(13):2826. doi: 10.3390/jcm10132826.
Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because right heart failure is the predominant cause of death in PAH patients. Given its wide availability and reduced cost, echocardiography is of paramount importance in the evaluation of the right heart in PAH. Several echocardiographic parameters have been shown to have prognostic implications in PAH; however, the role of echocardiography in the risk assessment of the PAH patient is limited under the current guidelines. This review discusses the echocardiographic evaluation of the RV in PAH and during therapy, and its prognostic implications, as well as the potential significant role of repeated echocardiographic assessment in the follow-up of patients with PAH.
肺动脉高压(PAH)的特征是肺血管受损,随后右心室(RV)适应增加的后负荷,最终导致右心室衰竭。由于右心衰竭是PAH患者的主要死亡原因,对PAH中右心室功能重要性的认识已大幅提高。鉴于超声心动图具有广泛的可用性且成本降低,它在PAH患者右心评估中至关重要。已显示几个超声心动图参数对PAH具有预后意义;然而,根据当前指南,超声心动图在PAH患者风险评估中的作用有限。本综述讨论了PAH患者及治疗期间右心室的超声心动图评估及其预后意义,以及重复超声心动图评估在PAH患者随访中的潜在重要作用。