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产后抑郁症:现状及生物标志物在其识别中的应用前景

Postpartum Depression: Current Status and Possible Identification Using Biomarkers.

作者信息

Yu Yi, Liang Hong-Feng, Chen Jing, Li Zhi-Bin, Han Yu-Shuai, Chen Jia-Xi, Li Ji-Cheng

机构信息

Central Laboratory, Yangjiang People's Hospital, Yangjiang, China.

Center for Analyses and Measurements, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, China.

出版信息

Front Psychiatry. 2021 Jun 11;12:620371. doi: 10.3389/fpsyt.2021.620371. eCollection 2021.

Abstract

Postpartum depression (PPD) is a serious health issue that can affect about 15% of the female population within after giving birth. It often conveys significant negative consequences to the offsprings. The symptoms and risk factors are somewhat similar to those found in non-postpartum depression. The main difference resides in the fact that PPD is triggered by postpartum specific factors, including especially biological changes in the hormone levels. Patients are usually diagnosed using a questionnaire onsite or in a clinic. Treatment of PPD often involves psychotherapy and antidepressant medications. In recent years, there have been more researches on the identification of biological markers for PPD. In this review, we will focus on the current research status of PPD, with an emphasis on the recent progress made on the identification of PPD biomarkers.

摘要

产后抑郁症(PPD)是一个严重的健康问题,大约15%的女性在产后会受到影响。它通常会给后代带来重大的负面后果。其症状和风险因素与非产后抑郁症有一定相似之处。主要区别在于PPD是由产后特定因素引发的,尤其是激素水平的生物学变化。患者通常通过现场或诊所的问卷调查来诊断。PPD的治疗通常包括心理治疗和抗抑郁药物。近年来,关于PPD生物标志物识别的研究越来越多。在这篇综述中,我们将关注PPD的当前研究现状,重点是PPD生物标志物识别方面的最新进展。

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本文引用的文献

1
Oxytocin and postpartum depression: A systematic review.
Psychoneuroendocrinology. 2020 Oct;120:104793. doi: 10.1016/j.psyneuen.2020.104793. Epub 2020 Jul 6.
2
Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next?
Front Endocrinol (Lausanne). 2020 May 14;11:236. doi: 10.3389/fendo.2020.00236. eCollection 2020.
3
Allopregnanolone in postpartum depression: Role in pathophysiology and treatment.
Neurobiol Stress. 2020 Feb 3;12:100212. doi: 10.1016/j.ynstr.2020.100212. eCollection 2020 May.
4
PPAR and functional foods: Rationale for natural neurosteroid-based interventions for postpartum depression.
Neurobiol Stress. 2020 Apr 19;12:100222. doi: 10.1016/j.ynstr.2020.100222. eCollection 2020 May.
5
Assessment of Postpartum Depression and Anxiety among Females Attending Primary Health Care Facilities in Qaliubeya Governorate, Egypt.
J Environ Public Health. 2019 Dec 26;2019:3691752. doi: 10.1155/2019/3691752. eCollection 2019.
6
DNA methylation biomarkers prospectively predict both antenatal and postpartum depression.
Psychiatry Res. 2020 Mar;285:112711. doi: 10.1016/j.psychres.2019.112711. Epub 2019 Nov 27.
7
Unraveling the Serum Metabolomic Profile of Post-partum Depression.
Front Neurosci. 2019 Aug 23;13:833. doi: 10.3389/fnins.2019.00833. eCollection 2019.
8
Bipolar disorders and bipolarity: the notion of the "mixity".
Psychiatr Danub. 2019 Sep;31(Suppl 3):434-437.
9
Neuroprotection of reduced thyroid hormone with increased estrogen and progestogen in postpartum depression.
Biosci Rep. 2019 Sep 3;39(9). doi: 10.1042/BSR20182382. Print 2019 Sep 30.
10
The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms.
Front Psychol. 2019 Jul 16;10:1033. doi: 10.3389/fpsyg.2019.01033. eCollection 2019.

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