• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

产后抑郁症:现状及生物标志物在其识别中的应用前景

Postpartum Depression: Current Status and Possible Identification Using Biomarkers.

作者信息

Yu Yi, Liang Hong-Feng, Chen Jing, Li Zhi-Bin, Han Yu-Shuai, Chen Jia-Xi, Li Ji-Cheng

机构信息

Central Laboratory, Yangjiang People's Hospital, Yangjiang, China.

Center for Analyses and Measurements, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, China.

出版信息

Front Psychiatry. 2021 Jun 11;12:620371. doi: 10.3389/fpsyt.2021.620371. eCollection 2021.

DOI:10.3389/fpsyt.2021.620371
PMID:34211407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8240635/
Abstract

Postpartum depression (PPD) is a serious health issue that can affect about 15% of the female population within after giving birth. It often conveys significant negative consequences to the offsprings. The symptoms and risk factors are somewhat similar to those found in non-postpartum depression. The main difference resides in the fact that PPD is triggered by postpartum specific factors, including especially biological changes in the hormone levels. Patients are usually diagnosed using a questionnaire onsite or in a clinic. Treatment of PPD often involves psychotherapy and antidepressant medications. In recent years, there have been more researches on the identification of biological markers for PPD. In this review, we will focus on the current research status of PPD, with an emphasis on the recent progress made on the identification of PPD biomarkers.

摘要

产后抑郁症(PPD)是一个严重的健康问题,大约15%的女性在产后会受到影响。它通常会给后代带来重大的负面后果。其症状和风险因素与非产后抑郁症有一定相似之处。主要区别在于PPD是由产后特定因素引发的,尤其是激素水平的生物学变化。患者通常通过现场或诊所的问卷调查来诊断。PPD的治疗通常包括心理治疗和抗抑郁药物。近年来,关于PPD生物标志物识别的研究越来越多。在这篇综述中,我们将关注PPD的当前研究现状,重点是PPD生物标志物识别方面的最新进展。

相似文献

1
Postpartum Depression: Current Status and Possible Identification Using Biomarkers.产后抑郁症:现状及生物标志物在其识别中的应用前景
Front Psychiatry. 2021 Jun 11;12:620371. doi: 10.3389/fpsyt.2021.620371. eCollection 2021.
2
Who is the main caregiver of the mother during the doing-the-month: is there an association with postpartum depression?在做月子期间,母亲的主要照顾者是谁:这与产后抑郁有关吗?
BMC Psychiatry. 2021 May 25;21(1):270. doi: 10.1186/s12888-021-03203-4.
3
Prevalence and predictors of postpartum depression by HIV status and timing of HIV diagnosis in Gauteng, South Africa.南非豪登省按 HIV 感染状况和 HIV 诊断时间划分的产后抑郁症流行率及其预测因素。
PLoS One. 2019 Apr 4;14(4):e0214849. doi: 10.1371/journal.pone.0214849. eCollection 2019.
4
Prevalence and Associated Factors of Postpartum Anxiety and Depression Symptoms Among Women in Shanghai, China.中国上海女性产后焦虑和抑郁症状的流行状况及相关因素。
J Affect Disord. 2020 Sep 1;274:848-856. doi: 10.1016/j.jad.2020.05.028. Epub 2020 May 23.
5
Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women.在一个种族多样化的产后女性样本中,生活中的不幸事件、精神病史和生物预测因素与产后抑郁症的关系。
Psychol Med. 2018 May;48(7):1190-1200. doi: 10.1017/S0033291717002641. Epub 2017 Sep 27.
6
Screening for Postnatal Depression in a Tertiary Care Hospital.三级护理医院中产后抑郁症的筛查
J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):72-6. doi: 10.1007/s13224-015-0766-x. Epub 2015 Oct 10.
7
Promising leads and pitfalls: a review of dietary supplements and hormone treatments to prevent postpartum blues and postpartum depression.有前景的线索和陷阱:预防产后抑郁和产后沮丧的膳食补充剂和激素治疗的回顾。
Arch Womens Ment Health. 2021 Jun;24(3):381-389. doi: 10.1007/s00737-020-01091-3. Epub 2020 Nov 17.
8
Mid-pregnancy vitamin D levels and postpartum depression.孕中期维生素D水平与产后抑郁症
Eur J Obstet Gynecol Reprod Biol. 2014 Aug;179:110-6. doi: 10.1016/j.ejogrb.2014.05.017. Epub 2014 Jun 2.
9
Postpartum depression treatment rates for at-risk women.高危女性产后抑郁症的治疗率。
Nurs Res. 2006 Mar-Apr;55(2 Suppl):S23-7. doi: 10.1097/00006199-200603001-00005.
10
Predicting Factors of Depression, Antidepressant Use and Positive Response to Antidepressants in Perinatal and Postpartum Women.围产期和产后女性抑郁症、抗抑郁药使用及对抗抑郁药阳性反应的预测因素
Clin Pract Epidemiol Ment Health. 2017 Jun 30;13:49-60. doi: 10.2174/1745017901713010049. eCollection 2017.

引用本文的文献

1
Epidemiology, pathophysiology, and interventions for postpartum depression: Systematic review.产后抑郁症的流行病学、病理生理学及干预措施:系统评价
World J Clin Cases. 2025 Oct 16;13(29):110948. doi: 10.12998/wjcc.v13.i29.110948.
2
Druggable Targets for Postpartum Depression: A Mendelian Randomization and Colocalization Study.产后抑郁症的可药物作用靶点:孟德尔随机化与共定位研究
Cell Mol Neurobiol. 2025 Jun 19;45(1):61. doi: 10.1007/s10571-025-01581-x.
3
Using the PowerMom Digital Health Platform to Support Prenatal Mental Health and Maternal Health Outcomes: Observational Cohort Study.使用PowerMom数字健康平台支持产前心理健康和孕产妇健康结局:观察性队列研究
JMIR Ment Health. 2025 May 22;12:e70151. doi: 10.2196/70151.
4
Risk Factors, Prognosis, Influence on the Offspring, and Genetic Architecture of Perinatal Depression Classified Based on the Depressive Symptom Trajectory.基于抑郁症状轨迹分类的围产期抑郁症的危险因素、预后、对后代的影响及遗传结构
Depress Anxiety. 2024 Mar 15;2024:6622666. doi: 10.1155/2024/6622666. eCollection 2024.
5
Prevalence and predictors of postpartum depression in women in Kosovo.科索沃女性产后抑郁症的患病率及预测因素
Womens Health (Lond). 2025 Jan-Dec;21:17455057251325944. doi: 10.1177/17455057251325944. Epub 2025 Mar 31.
6
The complex interaction between oestrogen receptor genes, oestradiol, and perinatal mood.雌激素受体基因、雌二醇与围产期情绪之间的复杂相互作用。
Dialogues Clin Neurosci. 2025 Dec;27(1):24-33. doi: 10.1080/19585969.2025.2482126. Epub 2025 Mar 21.
7
Social Support and Postpartum Depressive Symptoms in Portuguese Women: The Mediating Role of Emotion Regulation Difficulties.葡萄牙女性的社会支持与产后抑郁症状:情绪调节困难的中介作用
J Clin Med. 2024 Nov 26;13(23):7150. doi: 10.3390/jcm13237150.
8
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.产后抑郁小鼠模型中不同孕期累积应激、母婴分离及其对后代影响的比较
Heliyon. 2024 Jul 27;10(15):e35363. doi: 10.1016/j.heliyon.2024.e35363. eCollection 2024 Aug 15.
9
'Breakdown and healing' - adaptation experiences of postpartum nurses returning to work: a descriptive phenomenological study.“分解与愈合”——产后护士重返工作岗位的适应经历:一项描述性现象学研究
BMC Nurs. 2024 Jul 31;23(1):523. doi: 10.1186/s12912-024-02200-8.
10
From Breastfeeding to Support in Mothers' Feeding Choices: A Key Role in the Prevention of Postpartum Depression?从母乳喂养到支持母亲的喂养选择:在预防产后抑郁症方面的关键作用?
Nutrients. 2024 Jul 16;16(14):2285. doi: 10.3390/nu16142285.

本文引用的文献

1
Oxytocin and postpartum depression: A systematic review.催产素与产后抑郁症:系统评价。
Psychoneuroendocrinology. 2020 Oct;120:104793. doi: 10.1016/j.psyneuen.2020.104793. Epub 2020 Jul 6.
2
Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next?别孕烯醇酮,从神经调节剂转变为治疗剂:下一个是什么?
Front Endocrinol (Lausanne). 2020 May 14;11:236. doi: 10.3389/fendo.2020.00236. eCollection 2020.
3
Allopregnanolone in postpartum depression: Role in pathophysiology and treatment.别孕烯醇酮在产后抑郁症中的作用:在病理生理学及治疗中的角色
Neurobiol Stress. 2020 Feb 3;12:100212. doi: 10.1016/j.ynstr.2020.100212. eCollection 2020 May.
4
PPAR and functional foods: Rationale for natural neurosteroid-based interventions for postpartum depression.过氧化物酶体增殖物激活受体与功能性食品:基于天然神经甾体干预产后抑郁症的理论依据。
Neurobiol Stress. 2020 Apr 19;12:100222. doi: 10.1016/j.ynstr.2020.100222. eCollection 2020 May.
5
Assessment of Postpartum Depression and Anxiety among Females Attending Primary Health Care Facilities in Qaliubeya Governorate, Egypt.埃及盖勒尤卜省初级保健机构就诊女性产后抑郁和焦虑评估。
J Environ Public Health. 2019 Dec 26;2019:3691752. doi: 10.1155/2019/3691752. eCollection 2019.
6
DNA methylation biomarkers prospectively predict both antenatal and postpartum depression.DNA 甲基化生物标志物可前瞻性预测产前和产后抑郁症。
Psychiatry Res. 2020 Mar;285:112711. doi: 10.1016/j.psychres.2019.112711. Epub 2019 Nov 27.
7
Unraveling the Serum Metabolomic Profile of Post-partum Depression.解析产后抑郁症的血清代谢组学特征
Front Neurosci. 2019 Aug 23;13:833. doi: 10.3389/fnins.2019.00833. eCollection 2019.
8
Bipolar disorders and bipolarity: the notion of the "mixity".双相情感障碍和双相性:“混合性”的概念。
Psychiatr Danub. 2019 Sep;31(Suppl 3):434-437.
9
Neuroprotection of reduced thyroid hormone with increased estrogen and progestogen in postpartum depression.产后抑郁症中增加雌激素和孕激素以减少甲状腺激素的神经保护作用。
Biosci Rep. 2019 Sep 3;39(9). doi: 10.1042/BSR20182382. Print 2019 Sep 30.
10
The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms.别孕烯醇酮在孕期对产后焦虑症状的预测作用。
Front Psychol. 2019 Jul 16;10:1033. doi: 10.3389/fpsyg.2019.01033. eCollection 2019.