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“注视”角膜干细胞的特性、动态和区室化。

"Eyeing" corneal stem cell identity, dynamics, and compartmentalization.

机构信息

Mechanisms of Disease and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.

出版信息

Cell Stem Cell. 2021 Jul 1;28(7):1181-1183. doi: 10.1016/j.stem.2021.06.001.

Abstract

The mammalian cornea is maintained by the lifelong self-replenishing activity of its stem cells. In this issue of Cell Stem Cell, Altshuler et al. (2021) and Farrelly et al. (2021) identify two stem cell populations with diverse function and genetic signature, one "active" and one "quiescent," that support corneal health.

摘要

哺乳动物的角膜由其干细胞的终身自我更新活动维持。在本期《细胞-干细胞》杂志上,Altshuler 等人(2021 年)和 Farrellly 等人(2021 年)鉴定出两种具有不同功能和遗传特征的干细胞群体,一种是“活跃的”,另一种是“静止的”,它们共同支持角膜的健康。

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