Baylor Scott and White Health Department of Orthopedics, 2401 South 31st Street Temple, TX, 76508, USA.
Houston Methodist Hospital Department of Orthopedics, 6565 Fannin Street Houston, TX, 77030, USA.
Anaerobe. 2021 Oct;71:102412. doi: 10.1016/j.anaerobe.2021.102412. Epub 2021 Jul 1.
Parvimonas micra is an anaerobic, fastidious, gram positive organism commonly found in the oral cavity and gastrointestinal tract. It has been increasingly reported as the cause of septic arthritis of native joints, often times with delayed diagnosis leading to increased morbidity. Risk factors include immunosuppression, inflammation of the joint, and recent dental procedures or infections. It has been a historically difficult organism to culture. However, the development of and increasing use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has led to increased identification of P. micra. Common antibiotic susceptibilities, as well as data regarding susceptibilities in specific situations, have been reported, but susceptibility testing is required in all cases. Common treatments include clindamycin, penicillin, and metronidazole for six to ten weeks.
小韦荣球菌是一种常见于口腔和胃肠道的厌氧、难养的革兰阳性菌。它已被越来越多地报道为引起原发性关节感染性关节炎的原因，常因诊断延迟而导致发病率增加。危险因素包括免疫抑制、关节炎症以及最近的牙科手术或感染。该菌一直难以培养。然而，基质辅助激光解吸电离飞行时间质谱（MALDI-TOF-MS）的发展和日益广泛的应用，导致了对小韦荣球菌的鉴定增加。已报道了常见的抗生素敏感性，以及特定情况下的敏感性数据，但所有情况下都需要进行药敏试验。常见的治疗方法包括克林霉素、青霉素和甲硝唑治疗 6 至 10 周。
