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精神病患者物质使用的患病率及其最强预测因素的确定

Prevalence of Substance Use among Psychotic Patients and Determining Its Strongest Predictor.

作者信息

Mousavi Seyedeh Bentolhoda, Higgs Peter, Piri Negar, Sadri Ensieh, Pourghasem Matina, Jafarzadeh Fakhari Sanaz, Noroozi Mehdi, Miladinia Mojtaba, Ahounbar Elaheh, Sharhani Asaad

机构信息

Psychosis Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Department of Public Health, La Trobe University, Bundoora, 3083 Australia.

出版信息

Iran J Psychiatry. 2021 Apr;16(2):124-130. doi: 10.18502/ijps.v16i2.5812.

Abstract

Although comorbidity of psychotic disorders and substance use can lead to increase in mortality, less is known about the outbreak and predictors. Psychotic patients tend to be overlooked during assessment; hence, the possibility of an undertreated or missed condition such as increasing substance use. This investigation aimed to measure the prevalence of substance use in psychotic patients and to survey the powerful predictors. In a 1-year cross-sectional study, 311 psychotic patients were assessed using the Structured Interview Based on DSM-5 for diagnostic confirmation as well as questions surveying prevalence and possible predictors of substance use. Prevalence of substance use among psychotic patients was 37.9%. Several variables were identified as factors associated with drug abuse among the psychotic patients. These included male gender, younger age, being currently homeless, a history of imprisonment, and having family history of drug use. The strongest predictors of substance use, however, were family history of drug use, male gender, and being currently homelessness. Policymakers should note the importance of substance use among psychotic patients. Developing active screening strategies and comprehensive preventive plans, especially in the high-risk population, is suggested.

摘要

尽管精神障碍与物质使用的共病会导致死亡率上升,但对于其爆发情况及预测因素却知之甚少。在评估过程中,精神病患者往往被忽视;因此,存在治疗不足或漏诊某种情况(如物质使用增加)的可能性。本调查旨在衡量精神病患者中物质使用的患病率,并探究其有力的预测因素。在一项为期1年的横断面研究中,对311名精神病患者进行了评估,采用基于《精神疾病诊断与统计手册》第5版的结构化访谈进行诊断确认,并通过问卷调查物质使用的患病率及可能的预测因素。精神病患者中物质使用的患病率为37.9%。确定了几个与精神病患者药物滥用相关的变量因素。这些因素包括男性、年龄较小、目前无家可归、有监禁史以及有药物使用家族史。然而,物质使用最强的预测因素是药物使用家族史、男性以及目前无家可归。政策制定者应注意精神病患者中物质使用问题的重要性。建议制定积极的筛查策略和全面的预防计划,尤其是针对高危人群。

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