一名急性早幼粒细胞白血病患者在诱导缓解期间出现外周血幼稚细胞反弹并随后缓解。
Rebound peripheral blastosis with subsequent remission during remission induction in a patient with acute promyelocytic leukemia.
作者信息
Amato R, Kantarjian H, Walters R, Keating M
机构信息
Department of Hematology, University of Texas MD Anderson Hospital and Tumor Institute, Houston 77030.
出版信息
Cancer. 1988 Feb 15;61(4):650-3. doi: 10.1002/1097-0142(19880215)61:4<650::aid-cncr2820610405>3.0.co;2-9.
A patient with acute promyelocytic leukemia manifested peripheral blastosis with 50% peripheral blasts and an absolute blast count of 10,000/microliter 2 weeks after the start of induction chemotherapy. The subsequent disappearance of the peripheral and marrow blasts without further chemotherapy was noticed, and complete remission was achieved on day 25 of chemotherapy. The histologic and clinical implications of this phenomenon are discussed.
一名急性早幼粒细胞白血病患者在诱导化疗开始2周后出现外周血原始细胞增多，外周血原始细胞占50%，绝对原始细胞计数为10,000/微升。随后发现外周血和骨髓原始细胞在未进行进一步化疗的情况下消失，并在化疗第25天实现完全缓解。本文讨论了这一现象的组织学和临床意义。
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