Dorcé-Medard DO Jennifer, Okobi Md Okelue E, Grieb DO Jesse, Saunders DO Nzingha, Harberger Md Seneca
Family Medicine, Lakeside Medical Center, Belle Glade, USA.
Cureus. 2021 Jun 8;13(6):e15518. doi: 10.7759/cureus.15518. eCollection 2021 Jun.
One in six bisexual and gay men will be diagnosed with HIV in their lifetime (Human Rights Campaign, 2017). Without a vaccine or cure, prevention may be the best tool to control the HIV pandemic. Since 2012, the World Health Organization (WHO) recommends HIV pre-exposure prophylaxis (PrEP) for a high-risk population. To this day, in the United States (U.S.), the group with the highest risk is MSM (men who have sex with other men) that have condom-less sexual intercourse (Center for Disease Control and Prevention, 2019). In fact, in 2018, over 50% of all HIV infections occurred in MSM and members of the LGBT community. A systematic review was conducted using PubMed, Google Scholar, and Cochrane Library. The inclusive criteria were articles published from 2015-2020, focusing specifically on HIV PrEP among the members of the LGBTQ+ community. The keywords for our search were "Pre-exposure prophylaxis," "HIV," "men who have sex with other men" (MSM), "Bisexual," "transgender." A total of 25 articles met the inclusion criteria. About 50% of the articles focused on MSM while others highlighted bisexual and transgender women. Globally, PrEP is a priority. Programs to educate and promote its use are being developed, but challenges are present regarding access to PrEP and its maintenance for longer than 12 months. In the U.S., PrEP programs started in 2012, intending to promote and educate. Research shows that more than 60% of the high-risk patients are willing to try PrEP if they are correctly educated, showing that physicians were not doing a thorough job educating their patients. PrEP is essential for preventing the transmission of HIV among the LGBTQ+ subpopulation. Existing gaps need to be bridged to create or improve to educate high-risk populations and physicians on HIV PrEP.
每六名双性恋和男同性恋者中就有一人在其一生中会被诊断出感染艾滋病毒(人权运动组织,2017年)。由于没有疫苗或治愈方法,预防可能是控制艾滋病毒大流行的最佳工具。自2012年以来,世界卫生组织(WHO)建议对高危人群进行艾滋病毒暴露前预防(PrEP)。时至今日,在美国,风险最高的群体是进行无保护性行为的男男性行为者(MSM)(疾病控制与预防中心,2019年)。事实上,2018年,所有艾滋病毒感染病例中有超过50%发生在男男性行为者和LGBT社区成员中。使用PubMed、谷歌学术和考科蓝图书馆进行了一项系统综述。纳入标准是2015年至2020年发表的文章,特别关注LGBTQ+社区成员中的艾滋病毒暴露前预防。我们搜索的关键词是“暴露前预防”、“艾滋病毒”、“男男性行为者”(MSM)、“双性恋”、“跨性别者”。共有25篇文章符合纳入标准。约50%的文章关注男男性行为者,其他文章则突出了双性恋和跨性别女性。在全球范围内,暴露前预防是一个优先事项。正在制定教育和推广其使用的项目,但在获取暴露前预防药物及其维持使用超过12个月方面存在挑战。在美国,暴露前预防项目始于2012年,旨在进行推广和教育。研究表明,如果对高危患者进行正确教育,超过60%的患者愿意尝试暴露前预防,这表明医生在对患者进行教育方面工作并不彻底。暴露前预防对于预防LGBTQ+亚人群中的艾滋病毒传播至关重要。需要弥合现有的差距,以创建或改进针对高危人群和医生的艾滋病毒暴露前预防教育。