Kodzokov M A, Spot E V, Proskura A V, Gazimiev E S, A Damiev D, Gazimiev M A
Institute for Urology and Human Reproductive Health of I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Urologiia. 2021 Jun(3):82-86.
To study the influence of the technique of posterior reconstruction of the vesicourethral anastomosis (VUA) on the prevention of urinary incontinence after robotic-assisted radical prostatectomy (RARP).
A total of 67 patients (mean age 63 years) with localized prostate cancer were included in the study. All patients were divided into two groups. In the group 1 (n=32) the standard technique of the VUA was used, while in the group 2 (n=35) the two-layer posterior reconstruction was done. The impact of urinary incontinence on the quality of life was analyzed using the ICIQ-SF questionnaire 1, 3 and 6 months after operation. On postoperative days 5-7, all patients underwent cystography to assess the tightness of the VUA.
One month after RARP in the group 1 the mean score of ICIQ-SF questionnaire was 6.72, compared to 4.57 in group 2 (p=0.04). After 3 and 6 months the respective values were 3.8 vs. 2.3 (p=0.09) and 1.94 vs. 1.2 (p=0.23), respectively. Cystography revealed no extravasation of the contrast.
The results of a retrospective comparative study suggest that a two-layer posterior reconstruction of the VUA during RARP, being a simple method, provides better continence rate one month postoperatively compared to standard technique, although larger randomized clinical trials are needed.
研究膀胱尿道吻合术(VUA)后重建技术对机器人辅助根治性前列腺切除术(RARP)后预防尿失禁的影响。
本研究共纳入67例(平均年龄63岁)局限性前列腺癌患者。所有患者分为两组。第1组(n = 32)采用VUA标准技术,而第2组(n = 35)采用两层后重建技术。术后1、3和6个月使用ICIQ-SF问卷分析尿失禁对生活质量的影响。术后第5 - 7天,所有患者均接受膀胱造影以评估VUA的紧密程度。
RARP术后1个月,第1组ICIQ-SF问卷平均评分为6.72,第2组为4.57(p = 0.04)。3个月和6个月后的相应值分别为3.8对2.3(p = 0.09)和1.94对1.2(p = 0.23)。膀胱造影显示造影剂无外渗。
一项回顾性比较研究结果表明,RARP期间VUA的两层后重建作为一种简单方法,与标准技术相比,术后1个月的控尿率更高,尽管还需要更大规模的随机临床试验。