Yıldırım Jülide Gülizar, Bayık Temel Ayla
Department of Public Health Nursing, İzmir Katip Çelebi University Faculty of Health Sciences, İzmir, Turkey.
Department of Public Health Nursing, Ege University Faculty of Nursing, İzmir, Turkey.
Florence Nightingale J Nurs. 2020 Mar 6;28(1):13-22. doi: 10.5152/FNJN.2020.19020. eCollection 2020 Feb.
Warfarin, which is widely used for preventing thromboembolic events, can cause major and minor side effects. The aim of this trial is to evaluate the effect of nurse home-support program on self-management of patients receiving warfarin therapy.
A randomized, controlled trial was conducted using 36 selected and eligible patients who had 12-month home-visit follow-ups. The bleeding risk score, potential and preventable warfarin-related complications, patients' self-management behaviors, and anticoagulation satisfaction were examined. Data analyses were performed using parametric and nonparametric tests, split-plot analysis of variance, multiple regression analysis, and Bland and Altman plots test.
The bleeding risk score was an effective variable for assessing patient satisfaction (p<0.05). The self-management group demonstrated decreased bleeding risk at the end of the trial. The Duke Anticoagulation Satisfaction Scale mean score represents a statistically significant improvement in the self-management group (p<0.05). Patients' self-management behaviors improved significantly in the self-management group compared to the control group (p<0.05). The number of international normalized ratio values within the target range was significantly higher in the self-management group (174/432) than in the control group (82/432). The self-management group showed significant reductions in both thromboembolic events.
This trial demonstrated evidence that use of nursing home care is effective in developing self-management behaviors, improving patient satisfaction, and preventing complications in patients receiving warfarin therapy. This model could be easily adopted and implemented by home care services and health organizations.
华法林广泛用于预防血栓栓塞事件,但会引发严重和轻微的副作用。本试验旨在评估护士家庭支持项目对接受华法林治疗患者自我管理的影响。
采用随机对照试验,选取36名符合条件的患者进行为期12个月的家访随访。检查出血风险评分、潜在及可预防的华法林相关并发症、患者自我管理行为及抗凝满意度。数据分析采用参数检验和非参数检验、裂区方差分析、多元回归分析以及布兰德和奥特曼图检验。
出血风险评分是评估患者满意度的有效变量(p<0.05)。自我管理组在试验结束时出血风险降低。杜克抗凝满意度量表平均得分显示自我管理组有统计学意义的改善(p<0.05)。与对照组相比,自我管理组患者的自我管理行为有显著改善(p<0.05)。自我管理组国际标准化比值在目标范围内的次数(174/432)显著高于对照组(82/432)。自我管理组的血栓栓塞事件均显著减少。
本试验证明,在接受华法林治疗的患者中,使用家庭护理服务在培养自我管理行为、提高患者满意度和预防并发症方面是有效的。这种模式可被家庭护理服务机构和卫生组织轻易采用和实施。