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处理狭窄型克罗恩病:切除?缩窄成形术?扩张?

Managing Stricturing Crohn's Disease: Resect? Strictureplasty? Dilate?

机构信息

Division of Colon and Rectal Surgery, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA.

Department of Surgery, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA.

出版信息

J Laparoendosc Adv Surg Tech A. 2021 Aug;31(8):881-889. doi: 10.1089/lap.2021.0099. Epub 2021 Jul 15.

Abstract

Crohn's disease (CD) is a pan-intestinal disease of the gastrointestinal tract characterized by inflammatory, penetrating, and fibrostenotic phenotypes. Fibrostenotic stricture formation, without inflammatory or penetrating disease, is a common complication in CD, primarily affecting the small intestine and leading to small bowel obstruction. Because there is no medical therapy that prevents or reverses stricturing disease, endoscopic and surgical treatments are the mainstays of treatment, indicated to palliate symptoms and treat the complications. Endoscopic approaches include dilation, stricturotomy, and endoscopic stenting. Surgical options include resection, intestinal bypass, and various strictureplasty techniques. In this article, we will focus on the treatment of stricturing CD: specifically, the considerations important in choosing between different treatment options and technical tips to deal with complicated disease.

摘要

克罗恩病(CD)是一种胃肠道的全肠疾病,其特征为炎症性、穿透性和纤维狭窄性表型。纤维狭窄性狭窄的形成,没有炎症或穿透性疾病,是 CD 的常见并发症,主要影响小肠并导致小肠梗阻。由于没有预防或逆转狭窄性疾病的医学治疗方法,内镜和手术治疗是治疗的主要方法,旨在缓解症状和治疗并发症。内镜方法包括扩张、狭窄切开术和内镜支架置入。手术选择包括切除、肠旁路和各种狭窄成形技术。在本文中,我们将重点关注狭窄性 CD 的治疗:具体来说,就是在不同治疗选择之间进行选择时的重要考虑因素以及处理复杂疾病的技术技巧。

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