gamma-Aminobutyric acid (GABA) uptake systems in human frontal cortex.
作者信息
Sidhu H S, Munoz D G, Wood J D
机构信息
Department of Biochemistry, University of Saskatchewan, Saskatoon, Canada.
出版信息
Brain Res. 1987 Dec 1;435(1-2):334-6. doi: 10.1016/0006-8993(87)91619-2.
PMID:3427461
Abstract
Synaptosomes prepared from human frontal cortex possessed two uptake systems for gamma-aminobutyric acid (GABA) with Km values of 1.9 and 20.6 microM respectively, and with Vmax values of 0.15 and 0.78 nmol/min/mg protein respectively. In this respect, human tissue preparations differed from cortical synaptosomes from rodents in that a third, low-affinity GABA uptake system was not detectable in human synaptosomes.
摘要
Zotero 插件