Shenoy U A, Kushner J P, Schumann G B
Department of Pathology, University of Utah Medical Center, College of Medicine, Salt Lake City.
Diagn Cytopathol. 1987 Dec;3(4):323-5. doi: 10.1002/dc.2840030413.
Central nervous system (CNS) involvement in Hodgkin's disease is rare, but when the tumor extends into the CNS the route of tumor spread is similar to that seen in non-Hodgkin's lymphoma. Reed-Sternberg cells were identified in the cerebrospinal fluid (CSF) of a patient with Hodgkin's disease involving the CNS. Sequential cytologic examination of the CSF proved valuable in evaluating the efficacy of therapy. The ability to identify Reed-Sternberg cells in the CSF makes CSF cytology a useful adjunct in the management of patients with established or suspected CNS involvement of Hodgkin's disease.
中枢神经系统（CNS）受累于霍奇金淋巴瘤较为罕见，但当肿瘤扩散至中枢神经系统时，其扩散途径与非霍奇金淋巴瘤相似。在一名中枢神经系统受累的霍奇金淋巴瘤患者的脑脊液（CSF）中发现了里德-施特恩伯格细胞。对脑脊液进行连续细胞学检查在评估治疗效果方面被证明是有价值的。在脑脊液中识别里德-施特恩伯格细胞的能力使脑脊液细胞学成为管理已确诊或疑似中枢神经系统受累的霍奇金淋巴瘤患者的有用辅助手段。
