Department of Radiation Oncology, HM Hospitales, Madrid, Spain.
Department of Medical Physics, HM Hospitales, Madrid, Spain.
Br J Radiol. 2021 Aug 1;94(1124):20200809. doi: 10.1259/bjr.20200809.
Interest in low-dose radiotherapy (LD-RT) for the symptomatic treatment of nonmalignant conditions, including inflammatory and degenerative disorders of the joints and para-articular soft tissues, has increased substantially in recent years. In the present document, we provide a CT-based contouring atlas to help identify and delineate the most common osteoarticular regions susceptible to LD-RT.
The clinical efficacy of LD-RT is supported by a large body of evidence. However, there is no consensus on the parameters for contouring the planning target volume (PTV). Moreover, 3D simulation and planning should be the standard of care even for nonmalignant disorders. For this reason, the present guidelines were prepared to help guide PTV contouring based on CT images, with the same quality criteria for patient immobilization, treatment simulation, planning and delivery as those routinely applied for cancer radiotherapy.
PTV for radiotherapy requires precise identification of the target areas based on CT and other imaging techniques. Using a series of cases treated at our institution, we have defined the PTVs for each location on the simulation CT to establish the relationship between the image and the anatomical structures to be treated. We also specify the immobilization systems used to ensure treatment accuracy and reproducibility.
This comprehensive atlas based on CT images may be of value to radiation oncologists who wish to use LD-RT for the symptomatic treatment of degenerative or inflammatory osteoarticular diseases.
The recommendations and contouring atlas described in this article provide an eminently practical tool for LD-RT in non-malignant conditions, based on the same quality criteria recommended for all modern radiotherapy treatments in Spain.
近年来,人们对低剂量放射治疗(LD-RT)治疗非恶性疾病的兴趣大幅增加,包括关节和关节周围软组织的炎症和退行性疾病。在本文件中,我们提供了一个基于 CT 的轮廓图谱,以帮助识别和描绘最常见的易受 LD-RT 影响的骨关节炎区域。
LD-RT 的临床疗效有大量证据支持。然而,对于勾画计划靶区(PTV)的参数尚无共识。此外,即使对于非恶性疾病,三维模拟和计划也应成为标准治疗。出于这个原因,制定了本指南,以帮助根据 CT 图像指导 PTV 勾画,患者固定、治疗模拟、计划和交付的质量标准与常规癌症放射治疗相同。
放疗的 PTV 需要根据 CT 和其他成像技术精确识别靶区。使用我们机构治疗的一系列病例,我们已经定义了模拟 CT 上每个位置的 PTV,以建立图像与要治疗的解剖结构之间的关系。我们还指定了用于确保治疗准确性和可重复性的固定系统。
本基于 CT 图像的综合图谱可能对希望使用 LD-RT 治疗退行性或炎症性骨关节炎疾病的放射肿瘤学家有价值。
本文所述的建议和轮廓图谱基于西班牙所有现代放射治疗推荐的相同质量标准,为非恶性疾病的 LD-RT 提供了一个非常实用的工具。