Li Wenfeng, Mao Yuanshen, Gu Yufei, Lu Chao, Gu Xin, Hua Bao, Pan Weixin, Xi Qinghong, Xu Bin
Department of Urology, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, People's Republic of China.
Patient Prefer Adherence. 2021 Jul 16;15:1593-1600. doi: 10.2147/PPA.S321175. eCollection 2021.
Effective pain management is limited for patients during prostate biopsy (PBx). Touch support, such as hand holding, has stress-buffering benefits and effective analgesic effects. We conducted a prospective, single-center randomized clinical trial to assess whether hand holding can reduce patient anxiety, pain, and dissatisfaction during PBx.
Between April 2020 and October 2020, 120 male patients were randomized into three groups: a hand holding with relatives (HR) group, a hand holding with strangers (HS) group and a control group. A visual analog scale (VAS) was used for self-assessments of pain and satisfaction. Anxiety levels were quantified according to the State-Trait Anxiety Inventory (STAI). Hemodynamic changes were also measured.
The degree of pain and anxiety in the hand-holding groups was significantly better than that in the control group (<0.001), and the patients were more willing to undergo repeat PBx (=0.017). The anxiety levels in the HR group were significantly lower than those in the HS group (=0.019). During PBx, the changes in systolic blood pressure and heart rate in the hand-holding groups were more stable than those in the control group (<0.01), and the fluctuations in heart rate in the HR group were smaller than those in the HS group (<0.01).
Hand holding, especially with relatives, can promote incremental reductions in anxiety, pain and dissatisfaction in patients during PBx. Hence, we recommend hand holding with relatives as an effective adjunct during PBx.
前列腺活检（PBx）期间，患者的有效疼痛管理有限。触摸支持，如握住手，具有压力缓冲益处和有效的镇痛效果。我们进行了一项前瞻性、单中心随机临床试验，以评估握住手是否能减轻PBx期间患者的焦虑、疼痛和不满。
2020年4月至2020年10月期间，120名男性患者被随机分为三组：亲属握住手（HR）组、陌生人握住手（HS）组和对照组。使用视觉模拟量表（VAS）进行疼痛和满意度的自我评估。根据状态-特质焦虑量表（STAI）对焦虑水平进行量化。还测量了血流动力学变化。
握住手组的疼痛和焦虑程度明显优于对照组（<0.001），患者更愿意接受重复PBx（=0.017）。HR组的焦虑水平明显低于HS组（=0.019）。在PBx期间，握住手组的收缩压和心率变化比对照组更稳定（<0.01），HR组的心率波动小于HS组（<0.01）。
握住手，尤其是与亲属一起，可促进PBx期间患者焦虑、疼痛和不满的逐步减轻。因此，我们建议在PBx期间将与亲属握住手作为一种有效的辅助措施。
