1Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia; and.
Departments of2Neurological Surgery and.
J Neurosurg Spine. 2021 Jul 23;35(4):504-515. doi: 10.3171/2020.12.SPINE201527. Print 2021 Oct 1.
Rod fracture (RF) after adult spinal deformity (ASD) surgery is reported in approximately 6.8%-33% of patients and is associated with loss of deformity correction and higher reoperation rates. The authors' objective was to determine the effect of accessory supplemental rod (ASR) placement on postoperative occurrence of primary RF after ASD surgery.
This retrospective analysis examined patients who underwent ASD surgery between 2014 and 2017 by the senior authors. Inclusion criteria were age > 18 years, ≥ 5 instrumented levels including sacropelvic fixation, and diagnosis of ASD, which was defined as the presence of pelvic tilt ≥ 25°, sagittal vertical axis ≥ 5 cm, thoracic kyphosis ≥ 60°, coronal Cobb angle ≥ 20°, or pelvic incidence to lumbar lordosis mismatch ≥ 10°. The primary focus was patients with a minimum 2-year follow-up.
Of 148 patients who otherwise met the inclusion criteria, 114 (77.0%) achieved minimum 2-year follow-up and were included (68.4% were women, mean age 67.9 years, average body mass index 30.4 kg/m2). Sixty-two (54.4%) patients were treated with traditional dual-rod construct (DRC), and 52 (45.6%) were treated with ASR. Overall, the mean number of levels fused was 11.7, 79.8% of patients underwent Smith-Petersen osteotomy (SPO), 19.3% underwent pedicle subtraction osteotomy (PSO), and 66.7% underwent transforaminal lumbar interbody fusion (TLIF). Significantly more patients in the DRC cohort underwent SPO (88.7% of the DRC cohort vs 69.2% of the ASR cohort, p = 0.010) and TLIF (77.4% of the DRC cohort vs 53.8% of the ASR cohort, p = 0.0001). Patients treated with ASR had greater baseline sagittal malalignment (12.0 vs 8.6 cm, p = 0.014) than patients treated with DRC, and more patients in the ASR cohort underwent PSO (40.3% vs 1.6%, p < 0.0001). Among the 114 patients who completed follow-up, postoperative occurrence of RF was reported in 16 (14.0%) patients, with mean ± SD time to RF of 27.5 ± 11.8 months. There was significantly greater occurrence of RF among patients who underwent DRC compared with those who underwent ASR (21.0% vs 5.8%, p = 0.012) at comparable mean follow-up (38.4 vs 34.9 months, p = 0.072). Multivariate analysis demonstrated that ASR had a significant protective effect against RF (OR 0.231, 95% CI 0.051-0.770, p = 0.029).
This study demonstrated a statistically significant decrease in the occurrence of RF among ASD patients treated with ASR, despite greater baseline deformity and higher rate of PSO. These findings suggest that ASR placement may provide benefit to patients who undergo ASD surgery.
成人脊柱畸形(ASD)手术后的棒断裂(RF)发生率约为 6.8%-33%,与畸形矫正丢失和更高的再手术率相关。作者的目的是确定辅助附加棒(ASR)放置对 ASD 手术后原发性 RF 术后发生的影响。
本回顾性分析由资深作者对 2014 年至 2017 年接受 ASD 手术的患者进行研究。纳入标准为年龄>18 岁,包括骶骨固定在内的至少 5 个节段的器械化,以及 ASD 的诊断,其定义为骨盆倾斜度≥25°,矢状垂直轴≥5cm,胸椎后凸角≥60°,冠状 Cobb 角≥20°或骨盆入射角与腰椎前凸不匹配≥10°。主要焦点是至少有 2 年随访的患者。
在符合其他纳入标准的 148 名患者中,有 114 名(77.0%)获得了至少 2 年的随访并被纳入(68.4%为女性,平均年龄 67.9 岁,平均体重指数 30.4kg/m2)。62 名(54.4%)患者接受了传统的双棒结构(DRC)治疗,52 名(45.6%)患者接受了 ASR 治疗。总体而言,融合的平均节段数为 11.7,79.8%的患者接受了 Smith-Petersen 截骨术(SPO),19.3%接受了经椎弓根截骨术(PSO),66.7%接受了经椎间孔腰椎间融合术(TLIF)。DRC 组患者接受 SPO 的比例显著更高(DRC 组 88.7%,ASR 组 69.2%,p=0.010)和 TLIF(DRC 组 77.4%,ASR 组 53.8%,p=0.0001)。接受 ASR 治疗的患者基线矢状面失平衡更严重(12.0 比 8.6cm,p=0.014),ASR 组接受 PSO 的患者更多(40.3%比 1.6%,p<0.0001)。在完成随访的 114 名患者中,16 名(14.0%)患者报告发生 RF,RF 的平均时间为 27.5±11.8 个月。与接受 ASR 治疗的患者相比,接受 DRC 治疗的患者 RF 的发生率明显更高(21.0%比 5.8%,p=0.012),且平均随访时间相似(38.4 比 34.9 个月,p=0.072)。多变量分析表明,ASR 对 RF 的发生有显著的保护作用(OR 0.231,95%CI 0.051-0.770,p=0.029)。
本研究表明,在接受 ASR 治疗的 ASD 患者中,RF 的发生率有统计学显著降低,尽管基线畸形更大,PSO 发生率更高。这些发现表明,ASR 放置可能对接受 ASD 手术的患者有益。