Jin Haihao, Geng Jianshan
Department of Gastroenterology, Laiyang People's Hospital, Laiyang 265200, Shandong, China.
J Oncol. 2021 Jul 9;2021:4747843. doi: 10.1155/2021/4747843. eCollection 2021.
To compare the Clavien-Dindo grade and risk factors of complications after dual-port laparoscopic distal gastrectomy (DPLDG) and hand-assisted laparoscopic gastrectomy (HALG).
The clinical data of 775 patients who underwent DPLDG or HALG in our hospital from May 2016 to May 2019 were retrospectively reviewed, and the patients were divided into the DPLDG group ( = 386) and HALG group ( = 389) according to the surgical method to explore the risk factors of postoperative complications by grading their postoperative complications according to the Clavien-Dindo classification system and single-factor and multivariate analysis of the association between variables in clinical data and complications.
Compared with the HALG group, the DPLDG group had significantly shorter surgical time, less intraoperative blood loss, and better postoperative exhaust time ( < 0.05), with no significant difference in other clinical indicators between the two groups ( > 0.05); the postoperative complication incidence rate of DPLDG group was significantly lower than that of the HALG group; it was shown in the single-factor analysis that the age, tumor length, intraoperative blood loss, pathological stages, and surgical method were related to the postoperative complications, and the results of multivariate analysis indicated that DPLDG was the protective factor for reducing postoperative complications, while age no less than 60 years old and intraoperative blood loss no less than 180 ml were the independent risk factors leading to complications; after surgery, the PNI level values at T1, T2, and T3 of DPLDG group were significantly higher than those of the HALG group ( < 0.05); and at 1 month after surgery, both groups obtained significantly higher GLQI scores than before, and the GLQI score of the DPLDG group was significantly higher in the between-group comparison ( < 0.05).
The DPLDG has lower postoperative complication incidence rate than the HALG, but age no less than 60 years old and intraoperative blood loss not less than 180 ml are the independent risk factors for postoperative complications, so advanced prevention measures shall be taken to lower the incidence of complications.
比较双端口腹腔镜远端胃切除术(DPLDG)和手辅助腹腔镜胃切除术(HALG)后Clavien-Dindo分级及并发症危险因素。
回顾性分析2016年5月至2019年5月在我院接受DPLDG或HALG的775例患者的临床资料,根据手术方式将患者分为DPLDG组(n = 386)和HALG组(n = 389),按照Clavien-Dindo分类系统对术后并发症进行分级,并对临床资料中的变量与并发症之间的关联进行单因素和多因素分析,以探讨术后并发症的危险因素。
与HALG组相比,DPLDG组手术时间明显缩短,术中出血量少,术后排气时间更佳(P < 0.05),两组其他临床指标差异无统计学意义(P > 0.05);DPLDG组术后并发症发生率明显低于HALG组;单因素分析显示年龄、肿瘤长度、术中出血量、病理分期及手术方式与术后并发症有关,多因素分析结果表明DPLDG是降低术后并发症的保护因素,而年龄不小于60岁和术中出血量不小于180 ml是导致并发症的独立危险因素;术后,DPLDG组T1、T2和T3时的PNI水平值明显高于HALG组(P < 0.05);术后1个月,两组GLQI评分均明显高于术前,组间比较DPLDG组GLQI评分明显更高(P < 0.05)。
DPLDG术后并发症发生率低于HALG,但年龄不小于60岁和术中出血量不小于180 ml是术后并发症的独立危险因素,应采取积极预防措施降低并发症发生率。