反复肺部感染作为勒雪病的首发表现

Recurrent pulmonary infections as the first presentation of Letterer Siwe disease.

作者信息

Doya Leen Jamel, Dib Ghazal, Hassan Fouz

机构信息

Department of Pediatrics, Faculty of Medicine, Tishreen University Hospital, Lattakia, Syria.

Department of Dermatology, Faculty of Medicine, Tishreen University Hospital, Lattakia, Syria.

出版信息

Oxf Med Case Reports. 2021 Jul 21;2021(7):omab058. doi: 10.1093/omcr/omab058. eCollection 2021 Jul.

DOI:10.1093/omcr/omab058

PMID:34306724

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8297634/

Abstract

Langerhans cell histiocytosis (LCH) is a rare disease of unknown etiology that affects several organs. The fatal type of Langerhans cell histiocytosis is called Letterer Siwe disease (LSD) which is multisystem with a poor prognosis. Herein, we report a 20-month-old male who was admitted for recurrent pulmonary infections at the age of 10 months. Diagnostic workup revealed a Letterer-Siwe disease. The patient was treated with a good response.

摘要

朗格汉斯细胞组织细胞增多症（LCH）是一种病因不明的罕见疾病，可累及多个器官。朗格汉斯细胞组织细胞增多症的致死型称为勒-雪病（LSD），它累及多系统，预后较差。在此，我们报告一名20个月大的男性患儿，其在10个月大时因反复肺部感染入院。诊断检查显示为勒-雪病。该患者接受治疗后反应良好。