2日龄新生儿先天性疟疾：病例报告及文献综述
Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review.
作者信息
Kajoba Dickson, Ivan Egesa Walufu, Jean Petit Habonimana, Omar Matan Muhiadin, Laker Goretty, Mugowa Waibi William, Asiimwe Daniel
机构信息
Department of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, Uganda.
Department of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, Uganda.
出版信息
Case Rep Infect Dis. 2021 Jul 7;2021:9960006. doi: 10.1155/2021/9960006. eCollection 2021.
Congenital malaria is the presence of malaria parasites in a blood smear obtained from a neonate usually within 24 hours to 7 days of life. It has for long been regarded a rare condition. However, recent data indicate that congenital malaria complicates around 35.9% of live births globally, 0-37% in Sub-Saharan Africa and about 4-6.1% in Eastern Uganda. We present a 2-day-old neonate who presented with fever, irritability, and failure to breastfeed. Laboratory tests indicated that the neonate had a positive Giemsa-stained peripheral smear for , with a positive malaria rapid diagnostic test (MRDT) for . malaria. The mother had a negative peripheral film for malaria and a negative MRDT. The neonate was managed with intravenous artesunate with improvement.
先天性疟疾是指在出生后24小时至7天内从新生儿采集的血涂片中发现疟原虫。长期以来，它一直被视为一种罕见病症。然而，最近的数据表明，先天性疟疾在全球约35.9%的活产中并发，在撒哈拉以南非洲为0 - 37%，在乌干达东部约为4 - 6.1%。我们报告一例2日龄新生儿，出现发热、易激惹和拒乳。实验室检查显示，该新生儿吉姆萨染色外周血涂片疟原虫阳性，疟疾快速诊断试验（MRDT）阳性。母亲外周血涂片疟原虫阴性，MRDT阴性。该新生儿接受静脉注射青蒿琥酯治疗后病情好转。
Zotero 插件