Kunkel Samuel T, Gregory James J, Sabatino Matthew J, Borsinger Tracy M, Fillingham Yale A, Jevsevar David S, Moschetti Wayne E
Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Arthroplast Today. 2021 Jul 9;10:46-50. doi: 10.1016/j.artd.2021.05.012. eCollection 2021 Aug.
Risk-factor identification related to chronic opioid use after surgery may facilitate interventions mitigating postoperative opioid consumption. We evaluated the relationship between opioid use preceding total hip arthroplasty (THA) and total knee arthroplasty (TKA), and chronic use postoperatively, and the risk of chronic opioid use after total joint arthroplasty.
All primary THAs and TKAs performed during a 6-month period were identified. Opioid prescription and utilization data (in oxycodone equivalents) were determined via survey and electronic records. Relationship between preoperative opioid use and continued use >90 days after surgery was assessed via Chi-square, with significance set at < .05.
A total of 415 patients met inclusion criteria (240 THAs and 175 TKAs). Of the 240 THAs, 199 (82.9%) patients and of the 175 TKAs, 144 (82.3%) patients agreed to participate. Forty-three of 199 (21.6%) THA patients and 22 of 144 (15.3%) TKA patients used opioids within 30 days preoperatively. Nine of 199 (4.5%) THA and 10 of 144 (6.9%) TKA patients had continued use of opioids for >90 days postoperatively. Preoperative opioid consumption was significantly associated with chronic use postoperatively for THA ( = .011) and TKA ( = .024). Five of 43 (11.6%) THA and 4 of 22 (18.2%) TKA patients with preoperative opioid use had continued use for >90 days postoperatively. For opioid naïve patients, 2.6% (4/156) of THA and 4.9% (6/122) of TKA patients had chronic use postoperatively.
Preoperative opioid use was associated with nearly 5-fold and 4-fold increase in percentage of patients with chronic opioid use after THA and TKA, respectively. Surgeons should counsel patients regarding this risk and consider strategies to eliminate preoperative opioid use.
识别与术后长期使用阿片类药物相关的风险因素,可能有助于采取干预措施减少术后阿片类药物的使用量。我们评估了全髋关节置换术(THA)和全膝关节置换术(TKA)术前使用阿片类药物与术后长期使用之间的关系,以及全关节置换术后长期使用阿片类药物的风险。
确定在6个月期间进行的所有初次THA和TKA手术。通过调查和电子记录确定阿片类药物的处方和使用数据(以羟考酮当量计)。通过卡方检验评估术前使用阿片类药物与术后持续使用超过90天之间的关系,显著性设定为<0.05。
共有415例患者符合纳入标准(240例THA和175例TKA)。在240例THA患者中,199例(82.9%)患者,在175例TKA患者中,144例(82.3%)患者同意参与。199例THA患者中有43例(21.6%),144例TKA患者中有22例(15.3%)在术前30天内使用过阿片类药物。199例THA患者中有9例(4.5%),144例TKA患者中有10例(6.9%)术后持续使用阿片类药物超过90天。术前阿片类药物的使用量与THA(P = 0.011)和TKA(P = 0.024)术后长期使用显著相关。43例术前使用阿片类药物的THA患者中有5例(11.6%)术后持续使用超过90天,22例术前使用阿片类药物的TKA患者中有4例(18.2%)术后持续使用超过90天。对于未使用过阿片类药物的患者,2.6%(4/156)的THA患者和4.9%(6/122)的TKA患者术后长期使用阿片类药物。
术前使用阿片类药物分别使THA和TKA术后长期使用阿片类药物的患者比例增加近5倍和4倍。外科医生应就这种风险向患者提供咨询,并考虑采取策略消除术前使用阿片类药物的情况。