Chung Jun Seong, Kwak Han Deok, Ju Jae Kyun
Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
Ann Coloproctol. 2022 Dec;38(6):449-452. doi: 10.3393/ac.2021.00185.0026. Epub 2021 Jul 27.
Congenital factor V (FV) deficiency is a rare hemorrhagic disorder that can cause excessive bleeding during and after surgery in the affected patient. This report is the case of a patient who had FV deficiency with recurrent posthemorrhoidectomy bleeding treated with the hemostatic procedure and fresh frozen plasma (FFP) transfusions. A 45-year-old male patient had previously undergone hemorrhoidectomy for multiple hemorrhoids at a local hospital. Hemorrhoidectomy was successful; however, he was transferred to our hospital for evaluation of the origin of the recurrent posthemorrhoidectomy bleeding and underwent a hemostatic procedure. This bleeding was treated with coagulation using electrocautery, multiple sutures, and FFP transfusion (1,600 mL/day) for 7 consecutive days. The patient's plasma FV activity was 23%. Early detection of clotting factor deficiency in patients with hemorrhagic events after surgical treatments may prevent unnecessary procedures such as reoperations and minimize the cost of replacement therapy such as large-volume FFP transfusion.
先天性因子V(FV)缺乏症是一种罕见的出血性疾病,可导致受影响患者在手术期间及术后出现过度出血。本报告介绍了一例FV缺乏症患者,该患者在痔切除术后反复出血,采用止血程序和新鲜冰冻血浆(FFP)输注进行治疗。一名45岁男性患者此前在当地一家医院因多发性痔疮接受了痔切除术。痔切除术很成功;然而,他被转到我院评估痔切除术后反复出血的原因,并接受了止血程序。通过电灼、多次缝合和连续7天每天输注1600 mL FFP进行凝血治疗出血。患者的血浆FV活性为23%。在手术治疗后出现出血事件的患者中早期发现凝血因子缺乏症,可避免不必要的手术(如再次手术),并将大量FFP输注等替代治疗的费用降至最低。