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荧光先进视频皮肤镜检查:一种新的毛发和头皮评估方法。与毛发镜检查的比较。

Fluorescence advanced videodermoscopy: a new method of hairs and scalp evaluation. Comparison with trichoscopy.

机构信息

Dermatologic Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

出版信息

J Eur Acad Dermatol Venereol. 2021 Nov;35(11):2317-2323. doi: 10.1111/jdv.17558. Epub 2021 Aug 17.

Abstract

INTRODUCTION

Non-invasive diagnostic methods in clinical dermatology are widely used to reduce the need for invasive techniques, with great advantages in terms of cost and time. Dermoscopy is the reference test for the in vivo diagnosis of cutaneous lesions, and when it is performed on the scalp region it is named trichoscopy. Fluorescence advanced videodermoscopy (FAV) has been lately proposed as a new non-invasive method for the in vivo skin examination at high magnification, with cell-level resolution. So far, it has shown promising results for the assessment of melanocytic and vascular lesions and for the in vivo diagnosis of parasitosis.

OBJECTIVES

This observational study aims to perform, for the first time, a morphologic study of healthy scalp and scalp elementary lesions using FAV and to compare it with trichoscopy.

METHODS

We enrolled 90 healthy individuals for the evaluation of the scalp using FAV. Then, we recruited 53 patients with alopecia and collected images of the elementary lesions using FAV and trichoscopy.

RESULTS

Three hundred healthy scalp FAV images of different epidermal layers, papillary dermis, follicular ostia and healthy hair shafts were collected. Three hundred and eighty FAV and trichoscopic images of alopecic scalp elementary lesions were collected, showing that FAV provided a more detailed observation than trichoscopy, with higher magnification and cellular resolution.

CONCLUSION

Fluorescence advanced videodermoscopy may represent a new valid technique of support to trichoscopy, adding further information, increasing chances of diagnosis and decreasing the need of invasive procedures.

摘要

简介

临床皮肤科的非侵入性诊断方法被广泛用于减少对侵入性技术的需求,在成本和时间方面具有很大的优势。皮肤镜检查是皮肤病变的体内诊断的参考测试,当它在头皮区域进行时,被称为毛发镜检查。荧光高级视频皮肤镜检查(FAV)最近被提议作为一种新的非侵入性方法,用于高倍放大的皮肤检查,具有细胞级分辨率。到目前为止,它已经显示出在评估黑色素细胞和血管病变以及体内寄生虫病诊断方面的有前途的结果。

目的

本观察性研究旨在首次使用 FAV 对健康头皮和头皮初级病变进行形态学研究,并与毛发镜检查进行比较。

方法

我们招募了 90 名健康个体进行 FAV 头皮评估。然后,我们招募了 53 名脱发患者,并使用 FAV 和毛发镜检查收集初级病变的图像。

结果

收集了 300 张不同表皮层、乳头真皮、毛囊口和健康毛发轴的健康头皮 FAV 图像。共收集了 380 张脱发头皮初级病变的 FAV 和毛发镜检查图像,结果表明 FAV 比毛发镜检查提供了更详细的观察,具有更高的放大倍数和细胞分辨率。

结论

荧光高级视频皮肤镜检查可能代表一种新的支持毛发镜检查的有效技术,增加了更多的信息,增加了诊断的机会,并减少了对侵入性程序的需求。

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