Department of Orthopaedic Surgery, Loma Linda University Medical Center, Loma Linda, California.
JBJS Case Connect. 2021 Jul 28;11(3):01709767-202109000-00047. doi: e19.00538.
This is a case of a 44-year-old man with 10 years of history of painful callus-like swellings of bilateral index fingers. Sudden enlargement of the left index finger prompted biopsy, which revealed aggressive digital papillary adenocarcinoma (ADPA) that was treated with partial amputation. Biopsy of the contralateral finger revealed acanthotic skin with no evidence of malignancy.
Several case reports cite antecedent insult and chronic swelling before diagnosis. We describe a case of bilateral lesions with similar gross appearances, a long history of occupational repetitive trauma, and sudden enlargement of 1 lesion leading to the diagnosis of ADPA.
这是一例 44 岁男性,双侧食指有 10 年的疼痛性硬结样肿块病史。左食指突然肿大,行活组织检查,结果显示侵袭性指状乳头状腺癌(ADPA),行部分截肢治疗。对另一侧手指的活检显示棘皮病样皮肤,无恶性证据。
有几例病例报告指出,在诊断前有先前的损伤和慢性肿胀。我们描述了一例双侧病变,具有相似的大体外观,长期职业性重复创伤史,以及 1 个病变的突然肿大,导致 ADPA 的诊断。