[The role of the antioxidant system in the mechanism of adaptation to intensive noise].

It has been shown in the experiment with albino rats that the prolonged influence of stable noise (90 dB) results in a shift of the redox equilibrium in the thiol-disulphide and ascorbate systems of the adrenal gland and myocardium tissues towards oxidation and the activity of glucoso-6-phosphate dehydrogenase and superoxide dismutase decreases. A concept on the pathogenetic role of the redox equilibrium disturbance in the thiol-disulphide system, in particular, in the development of noise pathology is suggested.