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先天性无纤维蛋白原血症并伴有出血并发症患者的下肢动脉血栓的血管内治疗。

Endovascular Treatment for Lower-extremity Arterial Thrombosis in a Patient with Congenital Afibrinogenemia and a History of Bleeding Complications.

机构信息

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.

Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, Japan.

出版信息

Intern Med. 2022 Feb 1;61(3):361-364. doi: 10.2169/internalmedicine.7542-21. Epub 2021 Jul 30.

Abstract

Congenital afibrinogenemia is a rare autosomal recessive blood disorder that accompanies thrombotic complications and is associated with bleeding tendency. The management of these opposing complications remains a challenge. Endovascular treatment (EVT) for peripheral arterial thrombosis has not been described in previous studies. A 57-year-old man with congenital afibrinogenemia developed back pain and left lower leg pain. The cause of the pain was confirmed to be renal infarction and lower extremity arterial thrombosis by Doppler ultrasound and contrast-enhanced computed tomography. He was treated with EVT for the lower extremity arterial thrombosis, leading to an excellent short-term improvement without bleeding.

摘要

先天性无纤维蛋白原血症是一种罕见的常染色体隐性遗传性血液疾病,伴有血栓并发症,并伴有出血倾向。这些相反的并发症的处理仍然是一个挑战。以前的研究中没有描述过外周动脉血栓形成的血管内治疗(EVT)。一名 57 岁男性患有先天性无纤维蛋白原血症,出现背痛和左小腿疼痛。通过多普勒超声和增强计算机断层扫描证实疼痛的原因为肾梗死和下肢动脉血栓形成。他接受了下肢动脉血栓形成的 EVT 治疗,导致短期恢复良好,没有出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbc/8866793/c9d1ccbaf1dc/1349-7235-61-0361-g001.jpg

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